A5012755919- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Central Venous Catheters and Hemodialysis
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Cardiac, Anesthesia and Surgical Outcomes
- Alcohol Consumption and Health Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Gout, Hyperuricemia, Uric Acid
- Atherosclerosis and Cardiovascular Diseases
- Diabetes Treatment and Management
- Folate and B Vitamins Research
- Mechanical Circulatory Support Devices
Deutsches Herzzentrum München
2013-2022
Technical University of Munich
2013-2022
Deutsches Herzzentrum der Charité
2010-2022
Klinikum Ingolstadt
2022
St. Vincentius-Kliniken
2022
German Centre for Cardiovascular Research
2014-2021
Klinikum rechts der Isar
2009-2019
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2018
Christie's
2016
New York University
2012
Systematic investigation of restenosis after percutaneous coronary intervention (PCI) with bare metal stents (BMS) or first second generation drug eluting (DES) in large scale, broadly inclusive patient populations undergoing follow-up angiography represents a gap our scientific knowledge. We investigated the incidence angiographically proven and its predictors patients PCI stents.All successful implantation for de novo lesions from 1998 to 2009 at 6-8 months two centres Munich, Germany were...
Although biodegradable polymer drug-eluting stent (DES) platforms have potential to enhance long-term clinical outcomes, data concerning their efficacy are limited date. We previously demonstrated angiographic antirestenotic with a microporous, DES. In the current study, we hypothesized that at 12 months, its safety and would be non-inferior of permanent This prospective, randomized, open-label, active-controlled trial was conducted two tertiary referral cardiology centres in Munich,...
The role of vascular closure devices (VCD) for the achievement hemostasis in patients undergoing transfemoral coronary angiography remains controversial.To compare outcomes with use 2 strategies after diagnostic performed via access-a VCD-based strategy types devices, an intravascular device and extravascular device, vs standard manual compression. primary hypothesis to be tested was that femoral achieved through VCD is noninferior compression terms access-site complications. A secondary...
The investigation of no-reflow phenomenon after percutaneous coronary intervention (PCI) in patients with acute ST-segment-elevation myocardial infarction has therapeutic implications. We investigated the predictive factors, persistence time, and impact no reflow on salvage, ventricular function, mortality.The study included 1140 undergoing primary PCI paired scintigraphic examinations (before 7 to 14 days thereafter). After PCI, 108 had 1032 normal flow. median salvage index was 0.34...
Background— Durable polymer coatings have been implicated in mid- and long-term adverse events after drug-eluting stent implantation. A polymer-free dual-drug sirolimus- probucol-eluting a new generation permanent zotarolimus-eluting are recently developed technologies demonstrating encouraging results. Methods Results— In clinical trial with minimal exclusion criteria, we randomly assigned 3002 patients to treatment stents versus stents. The was designed demonstrate noninferiority of the...
Routine control angiography is a valuable tool with high-sensitivity in detecting restenosis after coronary stenting. However, the prognostic role of still controversial. We investigated impact on 4-year mortality patients undergoing routine stenting.All successful implantation stents for de novo lesions from 1998 to 2009 and 6-8 months at two centres Munich, Germany were studied. Restenosis was defined as diameter stenosis ≥50% in-segment area follow-up angiography. The primary outcome...
Whether prasugrel plus bivalirudin is a superior strategy to unfractionated heparin clopidogrel in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) has never been assessed specifically designed randomized trials.The Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 study an investigator-initiated, randomized, open-label, multicentre trial, test the hypothesis that STEMI planned PCI based on terms of net clinical...
Outcome data after extended long-term follow-up of patients with coronary artery disease treated drug-eluting stents (DES) in randomized clinical trials are scant. Performance differences among devices may be expected to emerge over time depending on whether stenting is done polymer-free or durable polymer DES. This study assessed the 10-year outcomes enrolled ISAR-TEST-5 (Test Efficacy Sirolimus- and Probucol-Eluting Versus Zotarolimus-Eluting Stents) trial. A total 3,002 were treatment...