A5086580570- Alzheimer's disease research and treatments
- Prion Diseases and Protein Misfolding
- Neuroinflammation and Neurodegeneration Mechanisms
- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Child Nutrition and Water Access
- Pluripotent Stem Cells Research
- Biomedical Ethics and Regulation
Johns Hopkins Medicine
2023-2024
Johns Hopkins University
2023-2024
Xi'an Jiaotong University
2023
Abstract The spread of prion‐like protein aggregates is a common driver pathogenesis in various neurodegenerative diseases, including Alzheimer's disease (AD) and related Tauopathies. Tau pathologies exhibit clear progressive spreading pattern that correlates with severity. Clinical observation combined complementary experimental studies has shown preformed fibrils (PFF) are seeds propagate pathology by entering cells templating misfolding aggregation endogenous Tau. While several cell...
The spread of prion-like protein aggregates is believed to be a common driver pathogenesis in many neurodegenerative diseases. Accumulated tangles filamentous Tau are considered pathogenic lesions Alzheimer's disease (AD) and related Tauopathies, including progressive supranuclear palsy, corticobasal degeneration. pathologies these illnesses exhibits clear hierarchical spreading pattern that correlates with severity
The marketing practices used by commercial milk formula (CMF) companies undermine breast feeding. However, it remains unclear how specific types of result in suboptimal feeding.We aimed to examine the associations CMF with breastfeeding outcomes, determine influencing pathways, changes perceptions and attitudes mothers towards CMF, impacts outcomes.A cross-sectional survey was conducted Beijing Jinan, China that mapped 2020. Mothers were interviewed about feeding for youngest child under age...