Vanessa Marfil

ORCID: 0009-0001-0738-863X
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About
Contact & Profiles
Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Laser Applications in Dentistry and Medicine
  • Protein Kinase Regulation and GTPase Signaling
  • Cancer-related gene regulation
  • Laser Material Processing Techniques
  • Ubiquitin and proteasome pathways
  • Biocrusts and Microbial Ecology
  • Alzheimer's disease research and treatments
  • Ocular and Laser Science Research
  • Epigenetics and DNA Methylation
  • Wnt/β-catenin signaling in development and cancer
  • Biochemical Acid Research Studies
  • Cancer-related Molecular Pathways

New Jersey Institute of Technology
2019-2020

Rutgers, The State University of New Jersey
2019-2020

City College of New York
2014-2016

Instituto de Investigación Sanitaria La Fe
2009-2014

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2014

Universitat Pompeu Fabra
2009

Alzheimer's disease (AD) is an age-associated disease. Mutations in the amyloid precursor protein (APP) may be causative or protective of AD. The presence two functionally redundant APP-like genes (APLP1/2) has made it difficult to unravel biological function APP during aging. nematode Caenorhabditis elegans contains a single family member, apl-1. Here, we assessed APL-1 on C. elegans' lifespan and found tissue-specific effects by overexpression APL-1. Overexpression neurons causes...

10.1111/acel.12509 article EN cc-by Aging Cell 2016-08-24

Laser microsurgery is a powerful tool for neurobiology, used to ablate cells and sever neurites in-vivo. We compare relatively new laser source two well-established designs. Rare-earth-doped mode-locked fibre lasers that produce high power pulses recently gained popularity industrial uses. Such systems are manufactured standards of robustness low maintenance requirements typical solid-state lasers. demonstrate an Ytterbium-doped femtosecond comparable in precision Ti:Sapphire (1-2...

10.1038/s41598-020-61479-0 article EN cc-by Scientific Reports 2020-03-11

Abstract Laser microsurgery is a powerful tool for neurobiology used to ablate cells and sever neurites in-vivo . We compare relatively new laser source two well-established designs. Rare-earth-doped mode-locked fibre that produce high power pulsed radiation recently gained popularity industrial uses. Such systems are manufactured at standards of robustness low maintenance requirements typical solid-state lasers. demonstrate an Ytterbium-doped femtosecond comparable in precision other...

10.1101/829242 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-11-04
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