- Genetics, Aging, and Longevity in Model Organisms
- Laser Applications in Dentistry and Medicine
- Protein Kinase Regulation and GTPase Signaling
- Cancer-related gene regulation
- Laser Material Processing Techniques
- Ubiquitin and proteasome pathways
- Biocrusts and Microbial Ecology
- Alzheimer's disease research and treatments
- Ocular and Laser Science Research
- Epigenetics and DNA Methylation
- Wnt/β-catenin signaling in development and cancer
- Biochemical Acid Research Studies
- Cancer-related Molecular Pathways
New Jersey Institute of Technology
2019-2020
Rutgers, The State University of New Jersey
2019-2020
City College of New York
2014-2016
Instituto de Investigación Sanitaria La Fe
2009-2014
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2014
Universitat Pompeu Fabra
2009
Alzheimer's disease (AD) is an age-associated disease. Mutations in the amyloid precursor protein (APP) may be causative or protective of AD. The presence two functionally redundant APP-like genes (APLP1/2) has made it difficult to unravel biological function APP during aging. nematode Caenorhabditis elegans contains a single family member, apl-1. Here, we assessed APL-1 on C. elegans' lifespan and found tissue-specific effects by overexpression APL-1. Overexpression neurons causes...
Laser microsurgery is a powerful tool for neurobiology, used to ablate cells and sever neurites in-vivo. We compare relatively new laser source two well-established designs. Rare-earth-doped mode-locked fibre lasers that produce high power pulses recently gained popularity industrial uses. Such systems are manufactured standards of robustness low maintenance requirements typical solid-state lasers. demonstrate an Ytterbium-doped femtosecond comparable in precision Ti:Sapphire (1-2...
Abstract Laser microsurgery is a powerful tool for neurobiology used to ablate cells and sever neurites in-vivo . We compare relatively new laser source two well-established designs. Rare-earth-doped mode-locked fibre that produce high power pulsed radiation recently gained popularity industrial uses. Such systems are manufactured at standards of robustness low maintenance requirements typical solid-state lasers. demonstrate an Ytterbium-doped femtosecond comparable in precision other...