A5087463840- Genomics and Rare Diseases
- BRCA gene mutations in cancer
- Genomic variations and chromosomal abnormalities
- Prenatal Screening and Diagnostics
- RNA modifications and cancer
- Health Services Management and Policy
- Radiation Dose and Imaging
- Child and Adolescent Health
- Child Development and Digital Technology
- CRISPR and Genetic Engineering
- Ethics in Clinical Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Genetically Modified Organisms Research
- Cell Adhesion Molecules Research
- Complementary and Alternative Medicine Studies
- Global Health Workforce Issues
- Child Nutrition and Feeding Issues
- Health Promotion and Cardiovascular Prevention
- Viral gastroenteritis research and epidemiology
- Infection Control in Healthcare
- Trauma and Emergency Care Studies
- Intimate Partner and Family Violence
- Global Public Health Policies and Epidemiology
- Healthcare Systems and Challenges
- Ultrasound in Clinical Applications
Temple University
2024-2025
Katherine Hospital
2024
Singleton Hospital
2021-2024
Temple College
2024
Emory University
2023
Cardiff and Vale University Health Board
2021
University Hospital of Wales
2014-2021
National Health Service Wales
2021
University of Alabama
2020
Kansas State University
2018-2020
In this article, we assess the 31 articles published in Basic and Applied Social Psychology (BASP) 2016, which is one full year after BASP editors banned use of inferential statistics. We discuss how authors collected their data, they reported summarized used data to reach conclusions. found multiple instances overstating conclusions beyond what would support if statistical significance had been considered. Readers be largely unable recognize because necessary information do so was not...
The open circular genome of human hepatitis B virus (HBV) is known to contain a partially double-stranded DNA with single-stranded gap region variable length. This structure the maintained by base-pairing 5' ends two stands, long or L(-) strand and short S(+) strand. By cloning, mapping, sequencing studies, we have localized three recombinational junctions integrated HBV in hepatoma samples, HT14 FOCUS. Breakpoints recombination derived from these results those others appear be clustered...
This study reviews the first 3 years of delivery National Health Service (NHS)-commissioned trio rapid whole genome sequencing (rWGS) service for acutely unwell infants and children in Wales.
Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental caused by heterozygous loss-of-function variants in SIN3A. We define the clinical and phenotypes related to SIN3A-haploinsufficiency 28 unreported patients. Patients with SIN3A adversely affecting protein function have mild intellectual disability, growth feeding difficulties. Involvement of multidisciplinary team including geneticist, paediatrician neurologist should be considered managing these described here...
Drawing on a series of interviews teacher residents, this study investigates residents’ foundational beliefs, the influences that shaped them, and extent to which they changed during their residencies. This has three primary findings. First, residents developed more sophisticated understanding what relational teaching entails. Second, increasingly recognized importance making real-world connections as motivator, though did not fully recognize students’ individual or cultural knowledge could...
Abstract Family violence is becoming increasingly visible in Australia, with many state and federal governments taking on more responsibility to address family its impacts those affected. Current efforts are focused practice frameworks, identifying responding risk factors, social justice frameworks including legislating against a range of jurisdictions addressing broadly the structural cultural forces that perpetuate further oppress victimised. not unique prevalence rates internationally...
One major concern in hospitalized patients is acquiring infections from pathogens borne on surfaces, patients, and healthcare workers (HCWs). Fundamental to controlling healthcare-associated identifying the sources of pathogens, monitoring processes responsible for their transmission, evaluating efficacy procedures employed restricting transmission.
Abstract ERBB4 encodes the tyrosine kinase receptor HER4, a critical regulator of normal cell function and neurodevelopmental processes in brain. One key ligands HER4 is neureglin-1 (NRG1), HER4-NRG1 signalling pathway essential neural crest migration, neuronal differentiation. Pharmacological inactivation has been shown to hasten progression epileptogenesis rodent models, heterozygous null mice are have cognitive deficits delayed motor development. Thus far there only single case report...
The sequences of two cloned genes from Drosophila which hybridize with tRNALys5 are reported. One gene, in plasmid pDt39, has a sequence corresponds to the tRNA. other pDt59R, differs three nucleotides pairs. Both plasmids transcribed vitro extracts Kc cells give full-sized tRNA precursors four additional at 5'-end as well truncated molecules containing 35 nucleotides. This premature termination occurs block T residues within mature coding region. Sequences flanking show little common except...
Abstract By clinical whole exome sequencing, we identified 12 individuals with ages 3 to 37 years, including three from the same family, a consistent phenotype of intellectual disability (ID), macrocephaly, and overgrowth adenoid tissue. All harbored rare heterozygous variant in ZBTB7A which encodes transcription factor Zinc finger BTB‐domain containing protein 7A, known play role lympho‐ hematopoiesis. ID was generally mild. Fetal hemoglobin (HbF) fraction elevated 2.2%–11.2% (reference...
Millennial consumers are an essential population segment who currently the third highest spenders in grocery aisles. Millennials often lumped into one homogenous group; however, they instead a diverse group comprised of unique characteristics. As producers increasingly adopting genetically modified (GM) crops, it is to understand how perceive technology. Using Situational Theory Publics, online survey was used capture character traits millennials and their perceptions toward GM foods....
A six week old, exclusively breast fed female infant, growing well along the 25th centile presented with a 24 hour history of decreased frequency and duration breastfeeding. Her mother was especially concerned, as her ‘feeding’, measured by duration, significantly according to ‘nursing tracker’: an iPhone application had been using since birth record feeds. This feeding prodromal RSV positive bronchiolitis, which developed hours after initial presentation, respiratory distress insufficient...
In the process of creating a care plan or finding placement for children, assessment their health and developmental needs will be undertaken. This can involve interpretation complex family history information may also include undertaking interpreting results genetic testing, when within professional guidelines. study explores opinions, knowledge about experiences adoption professionals in relation to testing Wales. Semi-structured qualitative interviews were conducted with six social workers...
<h3>Background</h3> Caring for severely ill infants and children necessitates the use of tremendous NHS resources. As a significant proportion unwell neonates have rare underlying genetic diagnosis, it is well recognised that testing can play an important role in their care. In recent years, rapid whole genome sequencing (rWGS) has been shown to positive impact on these patients. Specifically, previous research studies projects adopted rWGS approach reported increased diagnostic rate reduced...
Huanglongbing (HLB), commonly known as citrus greening, is a bacterial disease severely affecting the profitability and continuation of industry in Florida threatening other states well. Currently, only can be managed, not cured. Gene-based therapies, such GM science, have been identified viable long-term solution. However, consumer acceptance genetically modified food low their understanding new technologies largely dependent on what they receive through mass media. Therefore, purpose this...
GPs should help patients interpret nutritional information on packaged foods such as breakfast cereals, a leading obesity expert has suggested, because many so called healthy are not good for us we think. Professor Jane Wardle from University College London backed research the Consumers' Association that accuses manufacturers of cereal “lacing” their products with high levels sugar, salt, and fat. Professor pointed out food industry is driven to launch saltier, fattier, more sugary brands...
The long term care situation across the United Kingdom will “implode,” unless rest of follows Scotland's lead and funds personal for sick disabled people, official advisers have warned. Nine original 12 royal commissioners on elderly called English, Welsh, Northern Irish governments to scrap “artificial” distinction between nursing intimate help some patients need with dressing, washing, eating, or managing their continence. Since July 2002, people in Scotland been getting they free charge...