A5102643991- Peptidase Inhibition and Analysis
- Protein Degradation and Inhibitors
- Chromatin Remodeling and Cancer
- Ferroptosis and cancer prognosis
- Sleep and Wakefulness Research
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Neuroscience and Neuropharmacology Research
- Obstructive Sleep Apnea Research
- Liver Disease Diagnosis and Treatment
- Neonatal and Maternal Infections
- Sarcoma Diagnosis and Treatment
- MRI in cancer diagnosis
- Liver Disease and Transplantation
- Oral microbiology and periodontitis research
- Dyeing and Modifying Textile Fibers
- Ultrasound and Hyperthermia Applications
- Stoma care and complications
- RNA modifications and cancer
- Memory and Neural Mechanisms
- Neuroscience of respiration and sleep
- Pneumonia and Respiratory Infections
- Glioma Diagnosis and Treatment
- Gynecological conditions and treatments
- Immunotherapy and Immune Responses
Wuxi People's Hospital
2024
Weatherford College
2024
Ningbo University
2024
Ningbo University Affiliated Hospital
2023
Central South University
2023
Nantong University
2023
Wuhan University
2023
Southwest University
2023
Shanghai Sixth People's Hospital
2023
Shanghai Jiao Tong University
2023
BackgroundSleep disorders can profoundly affect neurological function. We investigated changes in social and anxiety-related brain functional connectivity induced by sleep deprivation, the potential therapeutic effects of general anaesthetics propofol sevoflurane rats.MethodsTwelve-week-old male Sprague–Dawley rats were subjected to deprivation for 20 h per day (from 14:00 10:00 next day) 4 consecutive weeks. They free from remaining during which they received (40 mg kg–1 i.p.) or (2% 2 h)...
Abstract Background Cell-based immunotherapy shows the therapeutic potential in sarcomas, addition to angiogenesis-targeted tyrosine kinase inhibitor (TKI) and immune checkpoint (ICI). Multi-antigen stimulated cell therapy-I (MASCT-I) technology is a sequential therapy for cancer, which composes of multiple antigen-loaded dendritic (DC) vaccines followed by adoptive transfer anti-tumor effector T-cells. Methods In this phase 1 study, we assessed MASCT-I plus camrelizumab (an ICI against...
Background: Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy with a high mortality rate poor prognosis. The exploration understanding of biomarkers will help to further improve diagnosis treatment OSCC. Methods: Tumor tissue samples from 319 OSCC patients were retrospectively collected, along their clinical information. In combination bioinformatics tools multiplex immunohistochemistry (mIHC) analyses, we evaluated NUP62CL protein expression its relationship...
To investigate the clinical value of contrast-enhanced ultrasound in prediction hepatic encephalopathy (HE) patients with hepatitis B cirrhosis after intrahepatic portal-systemic shunt via jugular vein. In this retrospective study, we collected data from 75 B, cirrhosis, and portal hypertension who underwent portosystemic February 2019 to 2022. The diagnostic instrument used was TOSHIBA Aplio500 color Doppler capabilities. trial group comprised 20 HE within 3 months postsurgery, while...
Glioblastoma (GBM) is characterized remarkably high tumors heterogeneity which contribute to its poor survival and effective therapies. We build the spatial habitats based on multiparametric physiologic MRI (diffusion-weighted perfusion-weighted MRI) describe intratumoral of gliomas explore possibility link between theses progression-free (PFS). This shows correspondence with molecular histological features images. also provide valuable information identify tumor progression areas that may...
Nasopharyngeal carcinoma (NPC) is one of the common malignant tumors, and its pathogenesis has not been fully clarified. This study aims to explore impact RNA interference on growth invasion NPC cells. Asparaginase isoaspartyl peptidase 1 (ASRGL1)-short hairpin(sh) expressing lentivirus was used investigate effect ASRGL1 knockdown cells (C666-1 SUN-1). The target shASRGL1 gene determined by mRNA protein expression in nasopharyngeal cells; cell proliferation viability, migration, invasion,...
Objective To investigate the clinical diagnosis and treatment value of hysteroscopy on patients with abnormal uterine bleeding.Method 60 bleeding were taken hypsteropic compared B ultrasonic histologic diagnosis.The confirmed cases also surgery.Results Endometrial polyps 23 (38.3％),endometrial hyperplasia disease 17 (28.3％),submucous myoma uterus 9 (15.0％),uterine cavity adhesion in 7 (11.7％),submucosal adenomyoma 2 (3.3％),chronic endometritis 1 case (1.7％) endometrial carcinoma...
The short shelf life of litchi is due to its rapid metabolism after being harvested. Refrigeration not a suitable method for preserving litchi, as the browning process that has been cryogenic will accelerate when it brought room temperature. This study introduces an alginate-based coating solution control post-harvest litchi. achieves this by simultaneously establishing crosslink and percolation networks, both which act barriers. network created using rod-like cellulose nanocrystals, possess...
Abstract Nasopharyngeal carcinoma (NPC) is a type of head and neck tumor that possesses invasion growth. This study aims to explore the impact RNA interference on growth nasopharyngeal cells. Asparaginase isoaspartyl peptidase 1 (ASRGL1)-short hairpin(sh) expressing lentivirus was used investigate effect ASRGL1 knockdown cells (C666-1). The target shASRGL1 gene determined by mRNA protein expression in cells; cell proliferation viability, migration, invasion, apoptosis, ATP levels oxidative...