A5016640567- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Urologic and reproductive health conditions
- Molecular Biology Techniques and Applications
- Boron Compounds in Chemistry
- Cardiac Imaging and Diagnostics
Carl von Ossietzky Universität Oldenburg
2019
Klinikum Oldenburg
2017-2019
Purpose: Sentinel lymph node (LN) dissection (sLND) using a magnetometer and superparamagnetic iron oxide nanoparticles (SPION) as tracer was successfully applied in prostate cancer (PCa). The feasibility of sentinel LN (SLN) visualization on MRI after intraprostatic SPION injection has been reported. In the present study, results preoperative identification SLNs outcome subsequent intraoperative magnetometer-guided sLND following were studied intermediate- high-risk PCa. Patients methods: A...
Radioisotope-guided sentinel lymph node dissection (sLND) has shown high diagnostic reliability in prostate (PCa) and other cancers. To overcome the limitations of radioactive tracers, magnetometer-guided sLND using superparamagnetic iron oxide nanoparticles (SPIONs) been successfully used PCa. This prospective study (SentiMag Pro II, DRKS00007671) determined accuracy intermediate- high-risk Fifty or PCa patients (prostate-specific antigen (PSA) ≥ 10 ng/mL and/or Gleason score 7; median PSA...
Background: Accurate histopathological evaluation of lymph nodes (LNs) is essential for reliable staging in prostate cancer.In routine practice, conventional techniques only examine parts the LN.Molecular nodal methods are limited by their high costs and extensive time requirement.One-step nucleic acid amplification (OSNA) determines metastatic status complete LN allows rapid intraoperative detection metastases.OSNA has been proposed diagnosis metastases from breast cancer quantifying CK19...
Targeted radioisotope-guided sentinel lymph node dissection (sLND) has shown high diagnostic accuracy in prostate cancer (PCa). To overcome the downsides of radioactive tracers, magnetometer-guided sLND using superparamagnetic iron oxide nanoparticles (SPIONs) was successfully applied PCa. This prospective study (SentiMag Pro II, DRKS00007671) determined intermediate- and high-risk Fifty or PCa patients (PSA≥10 ng/ml and/or Gleason score ≥7; median PSA 10.8 ng/ml, IQR...
You have accessJournal of UrologyProstate Cancer: Staging I1 Apr 2016PD42-01 MAGNETOMETER GUIDED SENTINEL LYMPHADENECTOMY AFTER INTRAPROSTATIC INJECTION OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES IN INTERMEDIATE- AND HIGH-RISK PROSTATE CANCER PATIENTS Alexander Winter, Svenja Engels, Philipp Goos, Marie-Christin Süykers, Stefan Gudenkauf, Rolf-Peter Henke, Holger Gerullis, and Friedhelm Wawroschek WinterAlexander Winter , EngelsSvenja Engels GoosPhilipp Goos SüykersMarie-Christin Süykers...
Derzeit erfolgt die präoperative SLN Diagnostik bei Prostata-Ca überwiegend mittels Lymphszintigrafie nach Applikation eines Radionuklid-Tracers. Ziel der Studie ist es, Eignung MRT als neues Schnittbildverfahren zur Identifizierung von zuvor erfolgter interstitieller, intraprostatischer Injektion SPION-Tracers darzulegen.
You have accessJournal of UrologyProstate Cancer: Staging II1 Apr 2018PD47-01 DETECTION OF CYTOKERATIN 19 EXPRESSION USING ONE-STEP NUCLEIC ACID AMPLIFICATION (OSNA): A NEW MOLECULAR METHOD FOR LYMPH NODE STAGING IN PROSTATE CANCER? Alexander Winter, Svenja Engels, Philipp Goos, Marie Christin Süykers, Rolf Peter Henke, Holger Gerullis, and Friedhelm Wawroschek WinterAlexander Winter More articles by this author , EngelsSvenja Engels GoosPhilipp Goos SüykersMarie Süykers HenkeRolf Henke...