A5072080616- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Epilepsy research and treatment
- Cardiac Structural Anomalies and Repair
- Sports injuries and prevention
- Mindfulness and Compassion Interventions
- Celiac Disease Research and Management
- Viral Infections and Immunology Research
- Abdominal Trauma and Injuries
- Anesthesia and Pain Management
- Enhanced Recovery After Surgery
- Cardiovascular Health and Risk Factors
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Urinary Bladder and Prostate Research
- Autoimmune and Inflammatory Disorders
- Dialysis and Renal Disease Management
- Diabetes Treatment and Management
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Occupational exposure and asthma
- Renal Diseases and Glomerulopathies
Robert Bosch (Germany)
2024
Bosch Health Campus
2024
Manchester University NHS Foundation Trust
2018-2020
St George's, University of London
2019
Barts Health NHS Trust
2019
Royal London Hospital
2019
Manchester Royal Infirmary
1997-2017
British Heart Foundation
2017
University of Manchester
2014-2017
Manchester University
2014
To investigate the haemodynamic effects of varying angle head up tilt.20 healthy subjects (12 female, eight male; mean (SD) age 33.6 (8.4) years) underwent tilt for five minutes to each four angles in random order, with a minute rest period at horizontal between angle. Forearm blood flow was measured using intermittent occlusion mercury strain gauge plethysmography two and minutes. Subjects continuous monitoring heart rate, systolic pressure (SBP), diastolic (DBP) by Finapres cardiac output...
AimsThe incidence of cardiac device infection (CDI) more than 12 months following complex implant (late infection) has not been extensively reported. Our objective was to compare both early (within months) and late rates implantation.
The diagnosis of epilepsy is complicated by various conditions that can mimic an epileptic seizure, and cardiovascular causing syncope may account for many cases so called secondary seizures.1 Convulsive syncope—that is, cerebral anoxic seizure activity to transient global impairment blood flow—can be difficult differentiate from epilepsy. differentiation however, important because treated effectively, especially when it due a bradycardia.1 In addition, long term anticonvulsant treatment...
Nalbuphine (0.3 mg.kg-1) and buprenorphine (2.5 micrograms.kg-1) were compared as part of a total intravenous anaesthesia regimen using propofol infusion in 60 patients undergoing laparoscopic cholecystectomy randomised double-blind study. Changes haemodynamic variables greater than 20% from the baseline noted. No difference was observed blood pressure but heart rate significantly lower group. Intra-operative bradycardia (heart < beat.min-1) occurred more often Recovery fast comparable with...
The development of the implantable cardiac pacemaker nearly 60 years ago represented a paradigm shift in control potentially lethal heart rhythms and has revolutionized lives those at risk sudden death from bradycardia. Subsequent technological developments have resulted devices that offer additional benefits to patients, including defibrillation resychronisation therapy. Previously, Cardiac Implantable Electronic Devices (CIEDs) relied on leads, either transvenous or epicardial, transmit...
Introduction: Head and Neck Cancer (HNC) accounts for 14.3% of all cancers in India 4.8% worldwide. In India, the most common sites are lip oral cavity (>80%), which more prevalent men than women. Histologically, cases Squamous Cell Carcinomas (SCC). The majority patients present with locally advanced stages, where surgery definitive chemoradiation therapy not possible palliative Radiotherapy (RT) is considered a treatment option better symptomatic relief improved Quality Life (QoL). Quad...
Background: The advent of medical alternatives to splenectomy, particularly the thrombopoietin receptor agonists (TPO‐RA) has seen reduction in its use for ITP. It is now generally reserved UK patients who fail multiple lines therapy. Aims: We aimed evaluate practices around splenectomy and long term response rates using data from ITP registry, a large national database primary cases set up 2007. Methods: analysed all registry entered December 2018. Data was studied on demographics, rates,...
Non-Q-wave infarction is associated with a significant incidence of and death. We followed 52 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) within three months non-Q-wave myocardial infarction. Thirty-eight had single-vessel disease, 12 double-vessel two triple-vessel disease. At follow-up at 28 +/- 8 months, all were alive. Three suffered recurrent during the period. Nine repeat angioplasty. Four bypass surgery for symptoms. Only 25% angina follow-up, but in...
Introduction: Cardiac resynchronisation therapy (CRT) has been reported to significantly reduce one–year mortality from 12.6 percent 9.7 when compared with optimal medical therpay for patients heart failure. We aimed establish whether improved one-year rates continue be observed in real world clinical practice. Methods: performed post-hoc analysis of all implanted new CRT devices at the Manchester Heart Centre between 04/01/2010 15/11/2011. Baseline characteristics were collected...
Background: Endocardial left ventricular (LV) pacing is an effective treatment option in patients with failed conventional coronary sinus lead.However, the major concern unknown long-term thromboembolic risk and much of data has come from a small number world leading centres.Whether LV endocardial safe hands wider EP community remains poorly established.We reviewed safety efficacy heart failure across 4 large UK centres.We examined if this cohort significant related to any patient or...
Abstract Background The diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) is often challenging and some structural abnormalities typical the disease may overlap with changes reflective cardiac adaptation to exercise. Purpose aim study was assess performance magnetic resonance (CMR) 2010 Task Force Criteria (TFC) in a cohort patients definite ARVC define highly trained athletes similar age sex. Methods We compared CMR features 43 (mean 49±17 years, 49% males, 32 (74%)...
Abstract Background/introduction Previous studies examining the utility of cardiac implantable electronic devices (CIEDs) to remotely monitor heart failure patients for decompensation have not demonstrated an impact on hard end-points. However, a key limitation these prior (REM-HF and MORE-CARE) has been stratify according their risk worsening (WHF) randomization (usual care vs active monitoring). We examined different approach, using single manufacturer’s remote monitoring platform, whereby...
Conference Abstract| June 01 1999 Pancreatic acinar cell injury after clot-dissolution therapy in myocardial infarction (MI) C Chaloner; Chaloner 1Pancreato-Biliary, Royal Infirmary, Manchester, UK Search for other works by this author on: This Site PubMed Google Scholar A Zaidi; Zaidi 2Cardiology, L Cotter; Cotter W Dollery; Dollery 3Emergency Medicine teams, K MacKway-Jones; MacKway-Jones Borgström; Borgström 4Department of Surgery, MAS, Malmö, Sweden JM Braganza Biochem Soc Trans (1999)...