Josien Levenga

ORCID: 0009-0001-9874-1119
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About
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Research Areas
  • Virus-based gene therapy research
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques

Abstract Cell culture has long been essential for preclinical modeling of human development and disease. However, conventional two‐dimensional (2D) cell fails to faithfully model the complexity found in vivo, novel drug candidates that show promising results 2D models often do not translate clinic. More recently, three‐dimensional (3D) have gained popularity owing their greater physiological relevance vivo biology. In particular, 3D spheroid are becoming widely used due ability mimic solid...

10.1002/cpz1.1121 article EN cc-by-nc-nd Current Protocols 2024-09-01
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