A5000978906- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Autoimmune Neurological Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Vestibular and auditory disorders
- Ion Transport and Channel Regulation
- Infectious Encephalopathies and Encephalitis
- Ophthalmology and Eye Disorders
- Receptor Mechanisms and Signaling
- Metabolism and Genetic Disorders
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Meningioma and schwannoma management
- Mitochondrial Function and Pathology
- Intracerebral and Subarachnoid Hemorrhage Research
- Ion channel regulation and function
- Glycogen Storage Diseases and Myoclonus
- RNA regulation and disease
- Neuropeptides and Animal Physiology
- Cardiac Imaging and Diagnostics
- Cytomegalovirus and herpesvirus research
- Polyoxometalates: Synthesis and Applications
- Spinal Hematomas and Complications
- Migraine and Headache Studies
- Oral and gingival health research
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2021-2025
Neurology, Inc
2025
Abstract Objective Typical semiology with associated 5As (Antecedent, Aura, Arrest, Automatisms, and Amnesia) is the prototypical seizure manifestation of temporal lobe epilepsy (TLE) in adults. However, patients TLE can present phenomenology referred to as “hypermotor TLE” (HMS‐TLE) which mimic extratemporal focal epilepsy. We studied clinico‐electrographic, imaging profile, surgical outcomes drug‐resistant HMS‐TLE patients. Methods analyzed ictal signs electroencephalography data who...
Abstract Background and Objectives: Persons with epilepsy (PWE) have poor dental hygiene, contributed by the severity of epilepsy, ignoring oral health, medications used. A continuing need exists for a better understanding effects antiseizure (ASMs) on health. Several studies shown older ASMs but there is lack those exploring side newer ASMs. Methods: cross-sectional study was conducted in which 69 PWE were compared 33 controls. structured questionnaire used to collect data demographics,...
Background The role of imaging in autoimmune encephalitis (AIE) remains unclear, and there are limited data on the utility magnetic resonance (MRI) to diagnose, treat, or prognosticate AIE. Purpose To evaluate whether MRI is a diagnostic prognostic marker for AIE assess its efficacy distinguishing between various subtypes. Material Methods We analyzed from 96 patients our prospective registry. sequences examined were FLAIR, diffusion, SWI, T2WI, ASL, contrast enhancement. Short-term outcomes...
Recurrent painful ophthalmoplegic neuropathy (RPON), previously called migraine, is a rare condition characterised by recurrent episodes of headache and ophthalmoplegia. We report case 11-year-old girl with ophthalmoplegia due to isolated right oculomotor nerve involvement. MR brain imaging showed enhancing lesion cisternal segment nerve. A possibility Tolosa Hunt syndrome was considered she treated glucocorticoids, followed azathioprine recurrence. In the fourth episode, developed migraine...
Objective: This prospective study aimed to quantify visual field defects (VFDs) along with other in ophthalmic functions after anterior temporal lobectomy (ATL) patients mesial lobe epilepsy (MTLE) and their impact on quality of life using a VFQ-25 questionnaire. Methods: Ophthalmic evaluation was done during pre-operative as well 3 months surgery. It included the Best Corrected Visual Acuity (BCVA), evaluation, colour vision examination, fundoscopy, extraocular movements diplopia charting....
Two genes likely to cause epilepsy, one silent and the other manifesting in a patient with drug-resistant can be quite unusual. Herein, we described case of 2-year-old girl who presented predominant language development delay, facial dysmorphism, refractory epilepsy normal neuroimaging metabolic profiles, which prompted us consider genetic etiology. Her test revealed two novel pathogenic mutations, Mediator complex subunit 13-like (MED13L) adhesion G protein-coupled receptor V1 (ADGRV1)....
Sir, ATP1A3 gene mutations are associated with alternating hemiplegia of childhood (AHC);[1] rapid-onset dystonia–parkinsonism (RDP);[2] and cerebellar ataxia, areflexia, pes cavus, optic atrophy, sensorineural hearing loss (CAPOS).[3] Rapid-onset (RDP) is characterized by an abrupt onset dystonia usually accompanied signs parkinsonism.[2] AHC transient episodes hemiplegia, dystonic attacks, paroxysmal abnormal ocular movements, seizures, autonomic dysfunction, intellectual disability.[1]...