A5111458868- Fish Ecology and Management Studies
- Fish Biology and Ecology Studies
- Genetic diversity and population structure
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Identification and Quantification in Food
- Genomics and Phylogenetic Studies
- Reproductive biology and impacts on aquatic species
- Estrogen and related hormone effects
- Aquaculture disease management and microbiota
- Gut microbiota and health
- Reproductive System and Pregnancy
- Ichthyology and Marine Biology
- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Fungal Diseases
- Crustacean biology and ecology
- Aquaculture Nutrition and Growth
- Diet and metabolism studies
- Peptidase Inhibition and Analysis
- MicroRNA in disease regulation
- Signaling Pathways in Disease
- Plant-Microbe Interactions and Immunity
- Environmental DNA in Biodiversity Studies
- Cancer, Hypoxia, and Metabolism
- Phytochemical and Pharmacological Studies
- Nutritional Studies and Diet
Sichuan University
2023-2025
University Health Network
2025
University of Toronto
1994-2025
Yangzhou University
2025
Jianghan University
2014-2024
Zhujiang Hospital
2024
Southern Medical University
2024
National Medical Products Administration
2024
West China Second University Hospital of Sichuan University
2023
Ministry of Agriculture and Rural Affairs
2019-2020
Several Pestalotiopsis-like species cause gray blight disease in tea plants, resulting severe production losses. However, systematic and comprehensive research on the diversity, geographical distribution, pathogenicity of pathogenic associated with plants China is limited. In this study, 168 isolates were obtained from diseased plant leaves 13 primary tea-producing provinces cities China. Based a multilocus (internal transcribed spacer, translation elongation factor 1-α, β-tubulin gene...
Calcineurin is an important signal-transducing enzyme in many cell types including T lymphocytes and a common target for the immunosuppressants cyclosporin A FK506. The crystal structures of both calcineurin [Griffith et al. (1995) Cell 82, 507−522; Kissinger Nature 378, 641−644] related enzyme, protein phosphatase-1 [Goldberg 376, 745−753], revealed that this class serine/threonine phosphatases contain their putative active sites binuclear metal center formed by Asn, two Asp, three His...
The orphan nuclear receptor steroidogenic factor-1 (SF-1) regulates the expression of several genes involved in reproductive function and development adrenal, gonads, pituitary gonadotropes. It also confers gonadotrope-specific glycoprotein hormone a subunit gene by binding to element (GSE). In this study, we have shown that SF-1 transactivates salmon gonadotropin II beta (sGTHII beta) expression. alone offered slight but significant enhancement on sGTHII promoter activity (7.2 +/- 0.6...
The role of testosterone (T) and 17 beta-estradiol (E2) in the control chinook salmon gonadotropin II beta subunit (sGTHII beta) gene was examined. Both E2 T specifically stimulated GTHII expression cultured juvenile rainbow trout pituitary cells. 5'-Flanking regions sGTHII linked to chloramphenicol acetyltransferase (CAT) vector were transfected into these cells, cultures treated with steroid hormones. Estrogen-stimulated CAT activity occurred constructs containing a 13-base pair estrogen...
Steroidogenic factor 1, a member of the fushi tarazu 1 (FTZ-F1) subfamily nuclear receptors, is key regulator in mammalian reproduction. From an embryonic complementary DNA library, zebrafish homolog FTZ-F1 (zFF1A) and alternatively spliced variant (zFF1B) were isolated. zFF1B represented C-terminally truncated version zFF1A. Whole mount situ hybridization reverse transcriptase-PCR analysis revealed that both zFF1A B transcripts present developing pituitaries, adult fish brain, gonads,...
Macrobrachium nipponense is a major farmed species freshwater shrimp in China and its genetic diversity of high value aquaculture. The construction the Three Gorges Project has slowed down water velocity Reservoir (TGR) made more clear, which favourable for survival reproduction M. . However, there are lack studies on populations TGR. In this study, mitochondrial COI gene sequences were used as molecular marker to analyze diversity, differentiation historical demography eight results showed...
Abstract Accurate assessment of glomerular filtration rate (GFR) is key in patients with cancer, to guide drug eligibility, adjust dosing systemic therapy, and minimize the risks undertreatment toxicity. Several aspects GFR evaluation cancer have been unclear, such as choice estimating equation overall lack data on reliability new markers, cystatin C. This uncertainty has led concerns that inaccurate estimation may a large impact clinical practice research. Recent brought important...
Background/Objectives: Freshwater shrimps of the family Atyidae, particularly hyperdiverse genus Caridina, are keystone decomposers in tropical aquatic ecosystems and valuable aquaculture resources. However, their evolutionary relationships remain unresolved due to conflicting morphological molecular evidence. Here, we sequenced characterized complete mitochondrial genome Caridina mariae (Tiger Shrimp), aiming (1) elucidate its genomic architecture, (2) reconstruct a robust phylogeny Caridea...
Objective: To explore the composition of gut microbiome, characteristics virulence factor genes and their relationship with liver metabolic inflammation in overweight or obese children. Methods: A case-control design was conducted. From children who visited West China Second University Hospital Sichuan for medical physical examinations between August 2021 April 2022, a total 23 (obesity group), 8 (overweight 22 healthy (control group) were recruited. The body mass index calculated after...
Salmonids are composed of anadromous and freshwater fishes, which is an important model for studying adaptive evolution. Herein, 49 salmonid complete mitochondrial genomes those two outgroups were used to infer a robust phylogeny the family Salmonidae. The BI RAxML phylogenetic trees based on 13 concatenated protein-coding genes showed well-supported nodes, topologies highly congruent. genes, ND2 , ND3 ND5 shown have significantly larger dN/dS ratios in species than Salmonidae, but CYTB gene...
Journal Article Functional analysis of estrogen-responsive elements in chinook salmon (Oncorhynchus tschawytscha) gonadotropin II beta subunit gene Get access D Liu, Liu 1Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada. Search other works by this author on: Oxford Academic Google Scholar F Xiong, Xiong C L Hew Endocrinology, Volume 136, Issue 8, 1 August 1995, Pages 3486–3493, https://doi.org/10.1210/endo.136.8.7628385 Published: 01 1995
The mechanism of bacterial community assembly has been the hot spot in field microbial ecology and it is difficult to quantitatively estimate influences different ecological processes. Here, a total 23 pairs planktonic sedimentary samples were collected from five lakes Wuhan, China. significant higher α-diversity (p < 0.001) β-diversity communities observed sediment than those water. Some phylum had linear relationships with comprehensive TSI (TSIc) by regression analysis. Non-metric...
High palmitic acid (PA) levels trigger metainflammation, facilitating the onset and progression of chronic metabolic diseases. Recently, exosomes were identified as new inflammation mediators. However, mechanism by which macrophage mediate PA-induced remains unclear.
The salmon pituitary expresses two distinct gonadotropins, gonadotropin I (GTHI) and II (GTHII). These hormones are synthesized in cells secreted at different stages during the reproductive cycle. To study transcriptional regulation of hormone-specific beta-subunit GTHII (sGTHII beta) gene, approximately 3.5 kilobases 5'-flanking region was characterized sequenced. specificity sGTHII beta examined by analyzing promoter activity homologous primary derived from spawning rainbow trout a...
The roots of Codonopis bulleynana Forest ex diels (cbFed), locally known as Tsoong, have been used a tonic food. Tsoong has wide range pharmacological effects, including anticancer efficacy. In the present study, activity and its potential molecular mechanisms were investigated. Isorhamnetin, flavonol aglycone, is important compound metabolite in Tsoong. It can promote apoptosis colon cancer cells through up-regulating apoptosis-related genes (Apaf1, Casp3 Casp9) because it blocks Hsp70...
We have isolated the genomic sequences encoding β subunit of chinook salmon gonadotropin II, using a IIβ cDNA probe. Southern blot analysis DNA suggests that there is single copy gene per haploid genome in salmon. The transcriptional unit 1.0 kilobase size and contains three exons interrupted by two introns. location first exon–intron junction within 5′untranslated region. second located between codons + 38 39, position comparatively conserved among previously characterized glycoprotein...
The prevalence of obese children in China is increasing, which poses a great challenge to public health. Gut microbes play an important role human gut health, and changes status are closely related obesity. However, how contribute obesity remains unclear. In our study, we performed shotgun metagenomic sequencing feces from 23 children, 8 overweight 22 control Chengdu, Sichuan, China.We observed distinct difference the microbiome that controls. Compared with controls, bacterial pathogen...
Abstract Background Cyprinidae, the largest fish family, encompasses approximately 367 genera and 3006 species. While they exhibit remarkable adaptability to diverse aquatic environments, it is exceptionally rare find them in seawater, with Far Eastern daces being of few exceptions. Therefore, serve as a valuable model for studying genetic mechanisms underlying seawater adaptation Cyprinidae. Results Here, we sequenced chromosome-level genomes two ( Pseudaspius brandtii P. hakonensis ),...