A5088459443- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Surgical site infection prevention
- Antifungal resistance and susceptibility
- Infective Endocarditis Diagnosis and Management
- Neutropenia and Cancer Infections
Postgraduate School of Molecular Medicine
2020
Grochowski Hospital
2020
Aims Calprotectin (CLP) is produced in neutrophils and monocytes released into body fluids as a result of inflammation or infection. The aim this study was to evaluate the utility blood synovial CLP diagnosis chronic periprosthetic joint infection (PJI). Methods Blood fluid samples were collected prospectively from 195 patients undergoing primary revision hip knee arthroplasty. Patients divided five groups: 1) total arthroplasty performed due idiopathic osteoarthritis (OA; n = 60); 2)...
Despite the availability of many highly accurate biomarkers and novel criteria, serum C-reactive protein (CRP) erythrocyte sedimentation rate (ESR) are still basis for diagnosing periprosthetic joint infection (PJI). This study aims to analyze influence different demographical clinical factors on cut-off values accuracy CRP ESR in chronic PJI. A total number 4757 patients (with ICD-10 codes T84.0 T84.5) operated between January 2014 December 2023 a single orthopaedic center were screened...
ObjectivesSonication of explanted prosthesis constitutes an element microbiological diagnostics. The aim performing this procedure is to remove biofilm and increase sensitivity Ultrasound used in medical purposes are low-frequency low-intensity. With wide range frequency which can be sonication process it necessary find the golden mean between dislodging planktonic bacteria sparing.Materials methodsThe study was determine least harming low-intensity ultrasound (35 kHz, 40 kHz or 53 kHz)...
Background: Despite the fact that many synovial fluid biomarkers have found application in routine diagnosis of periprosthetic joint infection (PJI), this process still remains a challenge for orthopaedic surgeons. To simplify process, fast point-of-care (POC) tests can be used during ambulatory visits and operating room conditions. However, before such routinely clinical practice, they require validation. The purpose present study was to evaluate diagnostic accuracy different POC detecting...
The aim of this study is to evaluate the value D-dimers in diagnosis periprosthetic joint infection (PJI). analysis was performed for revision total hip (rTHA) and knee arthroplasty (rTKA) together separately with two thresholds, one calculated by statistical methods second adopted from ICM 2018 definition. group comprised 133 patients who underwent rTHA or rTKA: 68 diagnosed according definition (PJI group) 65 aseptic implant loosening, instability, malposition, failure exclusion (aseptic...
Abstract Background D-lactic acid is a specific marker produced almost exclusively by bacterial species; thus, the appearance of this in synovial fluid may indicate periprosthetic joint infection (PJI). Recently, studies have investigated accuracy enzyme-linked laboratory tests that detect to diagnose PJI. However, our knowledge, no determined usefulness rapid strip diagnosis Questions/purposes (1) What best cutoff value for test diagnosing PJI? (2) are diagnostic accuracies (sensitivity,...
Despite improvements in surgical techniques, aseptics and prevention of infections, hospital site infections (SSI) still remain one the main reasons for failure therapeutic musculoskeletal surgery. This study aimed to conduct a retrospective analysis microbiological examinations determine pathogen sensitivity antibiotics as basis selecting methods preventing treating complicating infections.The is bacteriological tests performed departments Public Clinical Hospital Medical Centre...