A5115597382- Spine and Intervertebral Disc Pathology
- Renal cell carcinoma treatment
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Monoclonal and Polyclonal Antibodies Research
- MRI in cancer diagnosis
- Phagocytosis and Immune Regulation
- Smart Grid and Power Systems
- Infectious Diseases and Tuberculosis
- Intraocular Surgery and Lenses
- Nutrition, Health and Food Behavior
- Global Energy and Sustainability Research
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Immune cells in cancer
- Single-cell and spatial transcriptomics
- Land Use and Ecosystem Services
- RNA modifications and cancer
- Extracellular vesicles in disease
- Urinary Bladder and Prostate Research
- Hormonal Regulation and Hypertension
- Ocular Disorders and Treatments
- Anomaly Detection Techniques and Applications
- Renal and Vascular Pathologies
- Menopause: Health Impacts and Treatments
First Hospital of Shanxi Medical University
2025
Sun Yat-sen Memorial Hospital
2024-2025
Sun Yat-sen University
2023-2025
Shanxi Medical University
2024-2025
North China Electric Power University
2024
Tianjin University
2024
Peking University First Hospital
2024
Peking University
2024
Shenyang University of Technology
2024
West China Medical Center of Sichuan University
2024
Benign adrenal tumors comprise the majority of asymptomatic masses and are often associated with cortisol secretion, which increases risk obesity metabolic syndrome. Hormone secretion by these may confound prevailing epidemiologic findings, causal relationships among obesity, body fat, benign remain uncertain. Mendelian randomization (MR) uses genetic variation as an instrumental variable to simulate randomized controlled trials, thereby reducing confounding supporting relationships....
Efficient spectrum allocation in dynamic systems is a challenging problem, particularly for multi-hops transmissions. The inter-dependence between route selection and management makes it important to examine interaction the two corresponding performance com- plexity tradeoffs. In this paper, we explore design method- ologies: decoupled where these tasks are carried out independently by different protocol layers, collaborative that integrates them into single task. Experimental results show...
Developing and validating a modified parameter, the SYS-G angle (the between lower endplate of C2 upper C7 vertebrae), as feasible substitute for C2-C7 Cobb method in assessing cervical sagittal alignment exploring its reference range through large-scale retrospective study. The visibility C6, upper, endplates was graded compared. Baseline data such height, weight, body mass index (BMI), age, sex were analyzed their impact on endplate. Values C2-6 angle, C2-7 measured. intra- interobserver...
Background: Early-onset kidney cancer (EOKC) is often associated with genetic factors and a high risk of metastasis. However, there lack accurate prediction models for the prognosis EOKC. The aim this study to establish an effective nomogram predicting evaluating patients Methods: EOKC were selected from latest SEER database during 2004-2015. Patients between 2004 2014 randomly divided into training cohort validation at ratio 7:3, in 2015 used temporal external validation. Additionally, we...
Overactive Bladder (OAB), characterized by urinary urgency with frequency and nocturia, affects approximately 12 % of the adult female population's quality life. Estrogen, known for its role in modulating lower tract function, is commonly prescribed to alleviate urogenital symptoms menopausal women. However, efficacy oral estrogen treating OAB remains controversial. This study explores association between using data from National Health Nutrition Examination Survey (NHANES) 2005 2018....
Abstract Background The long-term survival benefit of immune checkpoint inhibitors (ICIs) in neoadjuvant and adjuvant settings is unclear for colorectal cancers (CRC) gastric (GC) with deficiency mismatch repair (dMMR) or microsatellite instability-high (MSI-H). Methods This retrospective study enrolled patients dMMR/MSI-H CRC GC who received at least one dose ICIs (neoadjuvant cohort, NAC) (adjuvant AC) 17 centers China. Patients stage IV disease were also eligible if all tumor lesions...
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe and fatal acute respiratory disease in humans. High fatality rates continued infectiousness remain a pressing concern for global health preparedness. Antibodies targeted at the receptor-binding domain (RBD) are major countermeasures against human viral infection. Here, we report four potent nanobodies MERS-CoV, which isolated from alpaca, especially potency of Nb14 is highest pseudotyped virus assay. Structural studies...
Understanding the mechanisms of invasion and metastasis in head neck squamous cell carcinoma (HNSCC) is crucial for effective treatment, particularly metastatic cases. In this study, we analyzed multicenter bulk sequencing comprehensive single-cell data from 702,446 cells, leading to identification a novel subtype cancer-associated fibroblasts (CAFs), termed Secreted Frizzled-Related Protein2 CAFs (SFRP2_CAFs). These originating smooth muscle display unique characteristics resembling both...
Background: This retrospective cohort study explores a practical approach to acquiring pathogenic microorganisms in patients with bone and joint infections. Methods: From Aug 2018 Mar 2022, 68 consecutive (87 cultures) infection were recruited this study. All cultures followed the Peking University First Hospital Procedure of Culturing Pathogenic for infection. Tissue samples obtained through fluoroscopy-guided biopsy or open debridement. divided into manual homogenization (MH), mixture...
<title>Abstract</title> Objective Developing and validating a novel parameter, the modified C2–C7 Cobb angle, as feasible substitute for traditional method in assessing cervical sagittal alignment, exploring its reference range through large-scale retrospective study. Methods The visibility of C6, C7 upper, lower endplates was graded compared. Baseline data such height, weight, body mass index (BMI), age, gender were analyzed their impact on endplate. Values C2-6 C2-7 angle measured. intra-...
Clear cell renal carcinoma (ccRCC) and ischemic stroke are critical global health challenges with a notable association. This study explores the correlation between tumor-related factors risk, aiming to construct predictive nomogram model for in ccRCC patients. We retrospectively analyzed data from patients who underwent nephrectomy at First Hospital of Shanxi Medical University January 1, 2013, May 31, 2022. The were randomly divided into training cohort (70%) validation (30%). Predictive...
Cranio-lenticulo-sutural dysplasia (CLSD) is a rare dysmorphic syndrome characterized by skeletal dysmorphism, late-closing fontanels, and cataracts. CLSD caused mutations in the SEC23A gene (OMIM# 607812) can be inherited either an autosomal dominant or recessive pattern. To date, only four have been reported to cause CLSD. This study aims identify disease-causing variants large cohort of congenital cataract patients, expand genotypic phenotypic spectrum CLSD, confirm association between...