A5000811098- Animal testing and alternatives
- Contact Dermatitis and Allergies
- Advancements in Transdermal Drug Delivery
- Insect and Pesticide Research
- Pressure Ulcer Prevention and Management
- Sexuality, Behavior, and Technology
- Skin Protection and Aging
- LGBTQ Health, Identity, and Policy
- Sex work and related issues
- Pesticide Exposure and Toxicity
- Body Contouring and Surgery
Unilever (United Kingdom)
1993-1997
University of Illinois Urbana-Champaign
1992
Since irritants are the major cause of contact dermatitis, it is important to identify those chemicals that possess significant ability skin irritation. This process must then be followed by risk assessment and management. Historically, animal tests have played a rôle in this process, but human volunteer studies increasing importance field. Where appropriate safely ethical controls place, testing can give data identities irritation hazard. To widest value, these not he flawed due...
Current regulations require that the skin irritation/corrosion potential of new chemicals is assessed in rabbit Draize test, although there are opportunities to use alternative methods identify most aggressive materials. Previously, we have proposed it possible la employ a strategy avoids animals and at same time delivers more relevant assessment irritation‐corrosion potential. The approach corrosive materials vitro then proceed human volunteer testing for irritation. In this study, 4‐h...
A major obstacle to the establishment of a protocol for in vivo irritant skin testing humans is apparent variability responses between individuals. This study threshold response normal human standard (sodium lauryl sulfate 0.3–10%), group 22 subjects, revealed marked interindividual variation their reaction. The results demonstrate that this phenomenon does exist and it will have be allowed future test systems or assays.
In an evaluation of the safety new chemicals, products containing them, or novel formulations existing chemicals which may come into contact with skin, it is important to incorporate assessment specially susceptible sub‐populations. Such a group represented by those who are more likely experience sensory effects such as stinging. Since these individuals easily and rapidly identifiable, we investigated whether they were also irritant. The primary purpose was discover ‘stingers’might represent...
Background The patterns of sexually transmitted infections (STIs) in populations may be influenced by the sexual mixing within population. We aimed to investigate assortative pattern bisexuality male-male partnerships. Methods This was a retrospective repeated cross-sectional study men with mostly regular male partners attending Melbourne Sexual Health Centre between 2011 and 2019. Data on practices, including their presence other male/female sex gender previous 3 12months, were collected...
Woisel, S. L.; Griffiths, H. A.; Stillman, R. J.; Slaughter, M. FACSM; Christ, C B.; Boileau, A. FACSM Author Information