- Hedgehog Signaling Pathway Studies
- Head and Neck Surgical Oncology
- Neurogenesis and neuroplasticity mechanisms
- Fibroblast Growth Factor Research
- Reconstructive Surgery and Microvascular Techniques
- Connective Tissue Growth Factor Research
- Reconstructive Facial Surgery Techniques
- Corneal surgery and disorders
- Kruppel-like factors research
- Cancer-related molecular mechanisms research
- Hippo pathway signaling and YAP/TAZ
- Ocular Diseases and Behçet’s Syndrome
- High Altitude and Hypoxia
- Retinal Diseases and Treatments
- Nerve injury and regeneration
- Bone health and treatments
- dental development and anomalies
- Bioactive Compounds in Plants
- RNA Research and Splicing
- Anesthesia and Neurotoxicity Research
- Natural product bioactivities and synthesis
- Glaucoma and retinal disorders
- Extracellular vesicles in disease
- Osteoarthritis Treatment and Mechanisms
Northwestern Polytechnical University
2022-2024
Air Force Medical University
2021-2024
Xijing Hospital
2021-2024
Zhejiang University
2024
Dampened peripheral clocks have been linked to osteoarthritis (OA), yet it is unclear whether drugging the clock can ameliorate OA. Given that RORs and REV‐ERBs mediate respectively, positive negative transcriptional feedback of master gene BMAL1 , we investigate agonist Nobiletin (NOB) SR1078, antagonist SR8278 enhance expression attenuate cartilage degeneration. NOB promoted elicited mitigating effects against IL‐1β‐induced degeneration explants, as evidenced by increased cellular density...
Background. Here, we report a case of male patient with bilateral focal choroidal excavation (FCE) and central serous chorioretinopathy (CSC). A 33-year-old man complained mild blurring vision in the right eye. Optical coherence tomography (OCT) revealed FCE both eyes, subretinal fluid eyes pigment epithelial detachment Standard laser fluence (50 J/cm2) was used eye, subthreshold micropulse (SML) simultaneously left Follow-up visits were recommended. At his last visit (5 months after...
In recent years, chondrocytes have been found to contain hemoglobin, which might be an alternative strategy for adapting the hypoxic environment, while potential mechanisms of that is still unclear. Here, we report expression characteristics and associated pathways hemoglobin in using single-cell RNA sequencing (scRNA-seq). We downloaded data normal people patients with osteoarthritis (OA) from Gene Expression Omnibus (GEO) database cells are unbiased clustered based on gene pattern....
Severe coloboma of ocular malignant neoplasms post-resection poses a reconstructive challenge to surgeons. To compare the practicability, manipulability and outcomes temporal (myocutaneous) flaps (TFs), forehead (supratrochlear artery/supraorbital artery) (FFs) buccal (facial (BFs) for periorbital defects reconstruction, retrospective case series was conducted evaluated between March 2014 2021. Patient demographics clinical parameters including age, gender, pathological diagnosis, operative...
Abstract Background : In dorsal root ganglion (DRG), satellite glial cells (SGCs) tightly surrounded neurons and modulated microenvironment sensory transmission. However, the biological properties of primary SGCs in culture were not fully understood. present study, we provided a method to harvest abundant high-purity from neonatal rats. Three supplementations containing Dulbecco’s Modified Eagle Medium (DMEM)/F12, DMEM high glucose (HG) Neurobasal-A (NB) used evaluate growth survival...