Hui Chu

ORCID: 0009-0003-1949-8187
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • CRISPR and Genetic Engineering
  • DNA and Biological Computing

Shandong University
2024

Zhongnan Hospital of Wuhan University
2024

Wuhan University
2024

State Key Laboratory of Cryptology
2024

San Francisco General Hospital
1988

University of California, San Francisco
1988

Abstract Phosphorothioation serves as a DNA backbone modification mechanism, wherein sulfur atom substitutes the nonbridging oxygen within phosphodiester, facilitated by gene products of dndABCDE or sspABCD. The combination with dndFGH forms bona fide defense system, where DndFGH protein complex exhibits nickase and translocase activities to prevent phage invasion. In this study, we identified that dndI, co-transcribed dndFGH, can independently couple iscS-dndBCDE an anti-phage system....

10.1093/nar/gkae1133 article EN cc-by Nucleic Acids Research 2024-11-29

In DNA sequences, we have the celebrated Watson-Crick complement T=A, A=T, C=G, and G=C. The phenomenon of secondary structure refers to tendency a single stranded sequence fold back upon itself, which is usually caused by existence two non-overlapping reverse substrings. property avoidance (SSA) forbids contain such substrings, it key criterion in design single-stranded sequences for both storage computing. this paper, prove that problem constructing SSA any given stem length m can be...

10.1109/tmbmc.2024.3396404 article EN IEEE Transactions on Molecular Biological and Multi-Scale Communications 2024-05-03
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