A5080457998- Immune Cell Function and Interaction
- Sarcoma Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Immune cells in cancer
- CAR-T cell therapy research
- Protein Degradation and Inhibitors
- Cancer, Hypoxia, and Metabolism
- Glaucoma and retinal disorders
- Advanced biosensing and bioanalysis techniques
- Corneal surgery and disorders
- Intracranial Aneurysms: Treatment and Complications
- RNA Interference and Gene Delivery
- Advanced Biosensing Techniques and Applications
- Cardiac tumors and thrombi
- Immunotherapy and Immune Responses
- Advanced Proteomics Techniques and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Laser Applications in Dentistry and Medicine
- Cerebrovascular and Carotid Artery Diseases
- Lymphoma Diagnosis and Treatment
- Uterine Myomas and Treatments
- Retinal Diseases and Treatments
- Biosimilars and Bioanalytical Methods
- Anorectal Disease Treatments and Outcomes
- Gothic Literature and Media Analysis
Rabindranath Tagore Medical College
2025
University of Pennsylvania
2017-2023
Children's Hospital of Philadelphia
2021-2023
All India Institute of Medical Sciences
2015-2023
Deen Dayal Upadhyay Hospital
2023
Philadelphia University
2022
Dr. Shroff’s Charity Eye Hospital
2018-2020
Cancer Hospital and Research Institute
2020
Cancer Institute (WIA)
2020
Christie's
2020
<i>Background: </i>Drug delivery across the blood-brain barrier (BBB) is a major limitation in treatment of central nervous system (CNS) disorders. Several approaches are being investigated to improve drug BBB. <i>Objective/Methods: </i>This review deals with role nanobiotechnology CNS delivery. The small size nanoparticles enables them penetrate BBB and facilitate drugs barrier. mechanisms involved this process various strategies used based on different types...
Cardio-oncology is an emerging field that studies cancer therapy-associated cardiotoxicities. Cardiotoxicity the second leading cause of death among survivors. Developing reliable and effective preclinical models for cardiotoxicity prediction prevention essential to improving long-term cardiac health patients. Zebrafish established model, study therapeutics potential cardiovascular toxicity. In this study, we are developing zebrafish pharmacogenomics experimental address complications...
Intraventricular cavernous h emangioma is a rare lesion. Dandy 1 reported his series of 5 cases angiomas the brain and ieviewed 44 in literature. In none these was lesion located inside lateral ventricles. 2 later 13 benign encapsulated tumours ventricles, which hemangioma. Schneider Liss 3 presented well hemangioma but only tumor right ventricle. The rarity this condition some unusual features case have prompted report. Case Report C.P., 15-year-old Italian boy, first seen on May 17th,...
Ewing sarcoma is the second most common pediatric bone cancer, with a 5-year survival rate for metastatic disease of only 20%. Recent work indicates that strongly correlated high levels tumor-infiltrating lymphocytes (TIL), whose abundance associated IFN-inducible chemokines CXCL10 and CCL5. However, tumor-intrinsic factors drive chemokine production TIL recruitment have not been fully elucidated. We previously showed ubiquitin-specific protease 6 (USP6) directly deubiquitinates stabilizes...
Biochips containing microarrays of genetic information promise to be important research tools in the postgenomic era. Because DNA microarray can contain many thousands samples, each representing a single gene, it is possible design chip complete gene set complex organism (30,000 60,000 genes). provide powerful way simultaneously analyze expression genes. This article describes and uses DNA.
Review Articles| December 13 2010 The Role of Nanobiotechnology in the Development Personalized Medicine Subject Area: General K.K. Jain PharmaBiotech, Basel, Switzerland Search for other works by this author on: This Site PubMed Google Scholar Med Princ Pract (2010) 20 (1): 1–3. https://doi.org/10.1159/000319928 Article history Received: March 31 Accepted: April 25 Published Online: Content Tools Views Icon contents Figures & tables Video Audio Supplementary Data Peer Share Facebook Twitter...
Purpose: To study the current profile of secondary glaucoma in all age groups patients presenting to a tertiary eye care hospital Northern IndiaMaterials and methods: In this retrospective study, files 5725 who were newly diagnosed have our centre from January 2014 December 2016 reviewed. Detailed data collected patient's records, including history, best-corrected visual acuity (BCVA), intraocular pressure (IOP), slit-lamp biomicroscopy findings, gonioscopy, fundus findings. Demographic...
Ewing sarcoma is a rare and deadly pediatric bone cancer for which survival rates treatment options have stagnated decades. has not benefited from immunotherapy due to poor understanding of how its immune landscape regulated. We recently reported that ubiquitin-specific protease 6 (USP6) functions as tumor suppressor in sarcoma, identified it the first cell-intrinsic factor modulate microenvironment (TME). USP6 induces intratumoral infiltration activation multiple innate lineages xenografted...
Preferences of service users is an important consideration for developing health-care services. This study aimed to assess the experiences patients with substance use disorders who were admitted a tertiary facility in India.This cross-sectional sectional recruited adult inpatients stayed period 7 days or more. The Picker Patient Experience questionnaire (PPE-15) was used gather information about views care received at center.Responses available from 113 inpatients. Majority participants...
A technique for sutureless anastamosis of the rat carotid arteries using Neodymium-YAG laser is described. It has certain advantages over con ventional suture and potential application in human extra- intracranial bypass surgery. Techniques repair injuries to small 1 end-to-end microvascular 2 have been described previously. end-to-side developed now.
While studies have identified a number of mutations in mantle cell lymphoma (MCL), the list may still be incomplete and contribution to pathogenesis remains unclear. We analyzed mutational landscape four biopsies obtained during an 8-year period from same patient with his normal cells serving as control; we also established line final stage disease. Numerous high allelic burden been all biopsies. large subset was seen only individual biopsies, core 21 persisted throughout This is maintained...
To ascertain the prevalence and clinical features of various types childhood glaucoma at a tertiary eye care hospital in Northern India.Retrospective chart review all children less than 16 years age with who presented from 1st April 2014 to 31st March 2019, was diagnosed have any subtype as per Childhood Glaucoma Research Network (CGRN) classification advised appropriate management.Out 405 glaucoma, 36% had primary whereas rest secondary glaucoma. Primary congenital (PCG) most common form...
Cancer is a growing problem in India, with over 1 million new cases estimated 2012 alone. In November 2013, organizers of the Indian Congress (a joint meeting four largest oncology associations India) invited panel mixed expertise including epidemiology, surgical oncology, health economics, environmental science, and systems to conduct round table on strategies for cancer prevention special focus non-tobacco risk factors. We present summary group recommendations here. While tobacco use...