A5038706448- Electron Spin Resonance Studies
- Lanthanide and Transition Metal Complexes
- Magnetism in coordination complexes
- Advanced NMR Techniques and Applications
- CO2 Reduction Techniques and Catalysts
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Processes in Materials Science
- Solid-state spectroscopy and crystallography
- Metallurgical Processes and Thermodynamics
- Glass properties and applications
- Metal Extraction and Bioleaching
- Atomic and Subatomic Physics Research
- Laser Material Processing Techniques
- Electrochemical Analysis and Applications
- Iron and Steelmaking Processes
- Catalysts for Methane Reforming
- Machine Learning in Materials Science
- Perovskite Materials and Applications
- Photorefractive and Nonlinear Optics
- Carbon dioxide utilization in catalysis
University of Waterloo
2023-2024
Goethe University Frankfurt
2013-2018
Russian Academy of Sciences
2013
Achieving large-scale electrochemical CO
Abstract The orchestrated interaction of transmembrane proteins with other molecules mediates several crucial biological processes. Detergent solubilization may significantly alter or even abolish such hetero‐oligomeric interactions, which makes observing them at high resolution in their native environment technically challenging. Dipolar electron paramagnetic resonance (EPR) techniques as pulsed electro–electron double (PELDOR) can provide very precise distances within biomolecules. To...
Pulsed electron paramagnetic resonance (EPR) spectroscopy is a valuable technique for the precise determination of distances between spin labels that are covalently attached to macromolecules. Nitroxides have commonly been utilised as tags biomolecules, but trityl radicals recently developed alternative labels. Trityls exhibit longer relaxation times and higher stability than nitroxides under in vivo conditions. So far, only used pulsed EPR dipolar (PDS) at X-band (9.5 GHz), Ku-band (17.2...
Dynamic nuclear polarization exploits electron spin to boost signal-to-noise in magic-angle-spinning (MAS) NMR, creating new opportunities materials science, structural biology, and metabolomics studies. Since protein NMR spectra recorded under DNP conditions can show improved spectral resolution at 180-200 K compared 110 K, we investigate the effects of AMUPol various deuterated TOTAPOL isotopologues on sensitivity these temperatures, using proline reproducibly prepared SH3 domain samples....
Dynamic nuclear polarization (DNP) enhances the sensitivity of solid-state NMR (SSNMR) spectroscopy by orders magnitude and, therefore, opens possibilities for novel applications from biology to materials science. This multitude opportunities implicates a need high-performance polarizing agents, which integrate specific physical and chemical features tailored various applications. Here, we demonstrate that biradical bTbK in complex with captisol (CAP), β-cyclodextrin derivative, host-guest...
PELDOR experiments on a Mn<sup>2+</sup>–nitroxide complex were performed. At 1.2 T the distance was determined by probing both spins. obtained at 6.4 provided as well orientation of nitroxide with respect to dipolar vector connecting
The ATP-binding cassette (ABC) transporter MsbA is an ATP-driven lipid-A flippase. It belongs to the ABC protein superfamily whose members are characterized by conserved motifs in their nucleotide binding domains (NBDs), which responsible for ATP hydrolysis. Recently, it was found that could catalyze a reverse adenylate kinase (rAK)-like reaction addition Both reactions connected and mediated same NBD domains. Here, structural foundations underlying were therefore explored using concerted...
Pulsed EPR dipolar spectroscopy is a powerful tool for determining the structure and conformational dynamics of biological macromolecules, as it allows precise measurements distances in range 1.5-10 nm. Utilization high-spin Mn2+ species spin probes distance significant interest, because they are biologically compatible endogenous numerous systems. However, to date experiments with this kind have been underexplored. Here we present pulsed electron double resonance (PELDOR also called DEER)...
Abstract The orchestrated interaction of transmembrane proteins with other molecules mediates several crucial biological processes. Detergent solubilization may significantly alter or even abolish such hetero‐oligomeric interactions, which makes observing them at high resolution in their native environment technically challenging. Dipolar electron paramagnetic resonance (EPR) techniques as pulsed electro–electron double (PELDOR) can provide very precise distances within biomolecules. To...
Accurate distances between two trityl paramagnetic tags site-specifically attached to DNA duplexes were measured by pulsed electron-electron double resonance spectroscopy at 180 and 260 GHz microwave frequencies. Up a threefold increase in the sensitivity of PELDOR measurements was achieved using shaped broad-band pulses.
Abstract Although intricate structural assemblies contribute to enhancing the activity of electrocatalytic CO 2 reduction (ECR) C 2+ products, blindly coupling multiple design strategies may not yield expected results, and even inhibit intrinsic catalytic sites. Therefore, elucidating promoting or inhibitory effects each strategy on ‐to‐C conversion clarify real active sites dynamic oxidation processes is paramount importance. Here, commonly used grain boundaries (GBs), states, alloying are...
High-spin gadolinium(III) and manganese(II) complexes have emerged as alternatives to standard nitroxide radical spin labels for measuring nanometric distances by using pulsed electron-electron double resonance (PELDOR or DEER) at high fields/frequencies. For certain complexes, particularly those with relatively small zero-field splitting (ZFS) short between the two metal centers, pseudosecular term of dipolar coupling Hamiltonian is non-negligible. However, in general, contribution from...
Recently, micro-resonator structures have demonstrated considerable enhancement of ESR spectroscopy. The high-quality factor and confined mode these resonators (cavities) lead to an enhanced spin-cavity interaction that both increase sensitivity for conventional measurements allow access experiments can investigate utilize effects associated with strongly interacting spin ensembles cavities. Superconducting micro-resonators are particularly interesting due their natural compatibility low...