A5080212207- Antimicrobial Peptides and Activities
- Healthcare and Venom Research
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Insect and Pesticide Research
- Toxin Mechanisms and Immunotoxins
Centre National de la Recherche Scientifique
2018-2024
CEA Paris-Saclay
2024
Institut de Biologie Intégrative de la Cellule
2018-2024
Université Paris-Saclay
2024
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2018-2024
Université Paris-Sud
2018
ABSTRACT Unlike most antimicrobial peptides (AMPs), the main mode of action subclass proline-rich (PrAMPs) is not based on disruption bacterial membrane. Instead, PrAMPs exploit inner membrane transporters SbmA and YjiL/MdtM to pass through enter cytosol specific Gram-negative bacteria, where they exert an inhibitory effect protein synthesis. Despite sharing a high proline arginine content with other characterized PrAMPs, PrAMP Bac5 has low sequence identity them. Here we investigated three...
The spatial organization of gut microbiota is crucial for the functioning ecosystem, although mechanisms that organize bacterial communities in microhabitats are only partially understood. insect Riptortus pedestris has a characteristic biogeography with multispecies community anterior midgut and monospecific population posterior midgut. We show region produces massively hundreds specific antimicrobial peptides (AMPs), Crypt-specific Cysteine-Rich (CCRs) have membrane-damaging activity...
Омский государственный медицинский университет 2 клинический кожновенерологический диспансер Цель -оценить эффективность препарата Аллергоферон® для купирования местных реакций при укусах насекомых.Материал и методы.Под наблюдением находились 80 пациентов (55 женщин 25 мужчин) в возрасте от 18 до 70 лет (средний возраст -34,8 ± 4,2 года), обратившихся к дерматологу по поводу не только укусов насекомых, но другой дерматологической патологии.При осмотре специалист выявил множество укусов,...