- Phytochemicals and Antioxidant Activities
- Tea Polyphenols and Effects
- Food Quality and Safety Studies
- Infant Nutrition and Health
- Phytochemistry and Biological Activities
- Photoacoustic and Ultrasonic Imaging
- Fatty Acid Research and Health
- Nanoplatforms for cancer theranostics
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Biochemical effects in animals
- Antioxidant Activity and Oxidative Stress
- Breastfeeding Practices and Influences
- Essential Oils and Antimicrobial Activity
- Digestive system and related health
- Phytoestrogen effects and research
- Ultrasound and Hyperthermia Applications
University of Michigan
2025
Purdue University West Lafayette
2010-2015
The pharmacokinetics, bioavailability, and regional brain distribution of polyphenols from apple-grape seed extract (AGSE) mixture bilberry were studied after 3 weeks dosing in weanling pigs.Weanling piglets treated for with extracts or extracts, using a physiological (27.5 mg/kg) supplement (82.5 dose. A 24-h pharmacokinetic study was conducted tissue harvested. Major flavan-3-ol flavonol metabolites including catechin-O-β-glucuronide, epicatechin-O-β-glucuronide,...
Recently, interest in the application of natural pigments to replace synthetic dyes beverages has grown. The present study investigates stability anthocyanin-rich grape and purple sweet potato (PSP) extracts photo- thermostresses ready-to-drink (RTD) beverage models including hot fill with various concentrations ascorbic acid, a preserved beverage, vitamin-enriched water beverage. Thermo- photostresses were induced at 40, 60, 80 °C 250, 500, 750 W/m(2), respectively. Qualitative quantitative...
Scope Metabolic syndrome has become an epidemic and poses tremendous burden on the health system. People with metabolic are more likely to experience cognitive decline. As obesity sedentary lifestyles common, development of early prevention strategies is critical. In this study, we explore potential beneficial effects a combinatory polyphenol preparation composed grape seed extract, Concord purple juice resveratrol, referred as standardized (SGP), peripheral well brain dysfunction induced by...
Histotripsy focused ultrasound treatment gives rise to systemic anti-tumor immune responses. We investigated whether histotripsy effects on immunosuppressive tumor hypoxia were a potential mechanism for these immunostimulatory effects. Immunocompetent or CD8-deficient C57BL/6 mice with flank B16F10 YUMM1.7 melanoma tumors underwent sham subtotal histotripsy. Tumor growth, cell infiltration, and intratumoral responses examined using flow cytometry fluorescence microscopy. Chemokine receptor...
Emerging evidence indicates that particular phytochemicals may have a role in infant nutrition and development, yet data on carotenoid flavonoid content of human milk remains sparse. Milk was longitudinally collected at 2, 4, 13, 26 weeks postpartum from twenty mothers each China, Mexico, the USA to determine variation composition by donor, lactation stage, country. Maternal neonatal plasma analyzed for carotenoids cohort 4 postpartum. Donor strongly predicted (p<0.01) total (mean ± SEM =...