- Cardiovascular Health and Risk Factors
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Immune cells in cancer
- Nutritional Studies and Diet
- Climate Change and Health Impacts
- Global Public Health Policies and Epidemiology
- Immune Cell Function and Interaction
- Retinal Diseases and Treatments
- Sleep and Work-Related Fatigue
- Generative Adversarial Networks and Image Synthesis
- Cancer Immunotherapy and Biomarkers
- Single-cell and spatial transcriptomics
- Health, Environment, Cognitive Aging
- Radiomics and Machine Learning in Medical Imaging
- Birth, Development, and Health
- Ophthalmology and Visual Impairment Studies
- AI in cancer detection
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Lishen (China)
2012
Shanghai Institute of Hypertension
2009
Abstract The exact function of M1 macrophages and CXCL9 in forecasting the effectiveness immune checkpoint inhibitors (ICIs) is still not thoroughly investigated. We investigated potential macrophage C‐X‐C Motif Chemokine Ligand 9 (CXCL9) as predictive markers for ICI efficacy, employing a comprehensive approach integrating multicohort analysis single‐cell RNA sequencing. A significant correlation between high improved overall survival (OS) objective response rate (ORR) was found. expression...
Aging in an individual refers to the temporal change, mostly decline, body’s ability meet physiological demands. Biological age (BA) is a biomarker of chronological aging and can be used stratify populations predict certain age-related chronic diseases. BA predicted from biomedical features such as brain MRI, retinal, or facial images, but inherent heterogeneity process limits usefulness body systems. In this paper, we developed multimodal Transformer–based architecture with cross-attention...
Abstract Background Myopia is a leading cause of visual impairment in Asia and worldwide. However, accurately predicting the progression myopia high risk remains challenge. This study aims to develop predictive model for development myopia. Methods We first retrospectively gathered 612 530 medical records from five independent cohorts, encompassing 227 543 patients ranging infants young adults. Subsequently, we developed multivariate linear regression algorithm predict Result The achieved an...
Objective: To explore the prevalence and level of risk factors cardiovascular disease among taxi drivers in Laiwu city compare with situation workers from other industries to identify key for intervention a worksite programme. Design methods: This is cross-sectional study onsite physical examinations city, Shandong province, China. All subjects on duty during examination period participated at survey. We measured body height, weight waist circumference, took blood pressure automatic machine,...
Objective: To explore the direct impact of outdoor temperature exposures on blood pressure (BP) across 31 provinces in China, based representative Chinese populationDesign and method: Data China Hypertension Survey study conducted from 2012 to 2015 was used analyze. season into warm cold season. sites were divided tropical, subtropical, temperate monsoon, continental alpine zones climate zones. A restricted cubic spline model applied delayed non-linear effects BP after controlling potential...