About
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Research Areas
- Genetics, Aging, and Longevity in Model Organisms
- Pluripotent Stem Cells Research
- Birth, Development, and Health
University of Lausanne
2024
SUMMARY In the last decade, cellular reprogramming of fully differentiated cells to pluripotent stem has become great interest. Importantly, by expression Oct4, Sox2, Klf4, and cMyc (OSKM) can ameliorate age-associated phenotypes in multiple tissues extend lifespan progeroid aged wild-type mice. Surprisingly, effects vivo have not been deeply investigated any other model organisms. Here, for first time, we induce C. elegans using a heat-inducible system at developmental adult stages. Similar...
10.1101/2024.05.03.592330
preprint
EN
cc-by-nc-nd
bioRxiv (Cold Spring Harbor Laboratory)
2024-05-04
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