K. G. Vaidya

ORCID: 0009-0003-9378-8318
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About
Contact & Profiles
Research Areas
  • Integrated Energy Systems Optimization
  • Renewable Energy and Sustainability
  • Global trade and economics
  • Advanced Thermodynamics and Statistical Mechanics
  • Fiscal Policy and Economic Growth
  • Public-Private Partnership Projects
  • Radiation Therapy and Dosimetry
  • Environmental Impact and Sustainability
  • PARP inhibition in cancer therapy
  • Electric Power System Optimization
  • Global Energy Security and Policy
  • Global Energy and Sustainability Research
  • Global Trade and Competitiveness
  • DNA Repair Mechanisms

University of Birmingham
1979-2024

Aston University
1979

Abstract Complex DNA damage (CDD), containing two or more lesions within one helical turns, is a signature of ionising radiation (IR) and contributes significantly to the therapeutic effect through cell killing. The levels complexity CDD increases with linear energy transfer (LET), however, specific cellular response this type critical proteins essential for repair currently unclear. We performed an siRNA screen ~240 identify those specifically involved in controlling survival high-LET...

10.1038/s41419-024-06541-9 article EN cc-by Cell Death and Disease 2024-02-17

10.1016/0140-9883(79)90050-1 article EN Energy Economics 1979-07-01
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