A5101854455- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Environmental Toxicology and Ecotoxicology
- Insect Resistance and Genetics
- Alzheimer's disease research and treatments
- Anesthesia and Sedative Agents
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Environmental remediation with nanomaterials
- Inflammation biomarkers and pathways
- Aquaculture disease management and microbiota
- Marine Biology and Environmental Chemistry
- bioluminescence and chemiluminescence research
- Acute Ischemic Stroke Management
- Cholinesterase and Neurodegenerative Diseases
- Urban Green Space and Health
- Extracellular vesicles in disease
- Chromium effects and bioremediation
- Spatial Cognition and Navigation
- Environmental Quality and Pollution
- Invertebrate Immune Response Mechanisms
- Aquatic Ecosystems and Phytoplankton Dynamics
- Cancer, Stress, Anesthesia, and Immune Response
- Medicinal Plants and Bioactive Compounds
Yantai University
2023-2025
Fujian Agriculture and Forestry University
2024
Ministry of Education
2024
Tianjin Medical University
2024
Nanjing University of Posts and Telecommunications
2024
Tianjin Third Central Hospital
2024
City University of Macau
2023
Tianjin University of Traditional Chinese Medicine
2020-2023
Shandong Agricultural University
2023
Tianjin University
2019
In Brief BACKGROUND: The etiology of postoperative cognitive decline (POCD) remains to be determined. Anesthetic isoflurane, but not desflurane, may induce neurotoxicity. However, the functional consequences these effects have been assessed. We therefore performed a pilot study determine isoflurane and desflurane on function in humans. METHODS: subjects included patients who had lower extremity or abdominal surgery under spinal anesthesia alone (S, n = 15), plus (SD, (SI, 15) by...
Some anesthetics have been suggested to induce neurotoxicity, including promotion of Alzheimer's disease neuropathogenesis. Nitrous oxide and isoflurane are common anesthetics. The authors set out assess the effects nitrous and/or on apoptosis beta-amyloid (Abeta) levels in H4 human neuroglioma cells primary neurons from naïve mice.The or were exposed 70% 1% for 6 h. conditioned media harvested at end treatment. Caspase-3 activation, apoptosis, processing amyloid precursor protein, Abeta...
Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation increase Aβ accumulation. In addition, recent studies suggest that may directly promote formation cytotoxic soluble oligomers, which thought be key pathological species in AD. contrast, propofol, most commonly used intravenous anesthetic, reported have neuroprotective effects. We therefore set out compare effects...
Accumulation of β-amyloid protein (Aβ) and tau is the main feature Alzheimer disease neuropathogenesis. Anesthetic isoflurane, but not desflurane, may increase Aβ levels in vitro animals. Therefore, we set out to determine effects isoflurane desflurane on cerebrospinal fluid (CSF) humans.The participants were assigned into spinal anesthesia (N=35), plus (N=33), or (N=38) group by randomization using computer-generated lists. Pre- postoperative human CSF samples obtained through an inserted...
Biointerfacing nanomaterials with cell membranes has been successful in the functionalization of nanoparticles or nanovesicles, but microbubble remains challenging due to unique conformation lipid monolayer structure at gas-liquid interface that provides insufficient surfactant activity. Here, we describe a strategy rationally regulate activity platelet membrane vesicles by adjusting ratio proteins lipids through fusion synthetic phospholipids (i.e., liposomes). A "platesome" optimized...
Aging is the primary risk factor for onset of Alzheimer's disease (AD). Inflamma-aging a major feature in process aging, and chronic neuroinflammation caused by inflamma-aging closely related to AD. As main participant neuroinflammation, polarization microglia (MG) could influence development neuroinflammation.
Abstract Biointerfacing nanomaterials with cell membranes has been successful in the functionalization of nanoparticles or nanovesicles, but microbubble remains challenging due to unique conformation lipid monolayer structure at gas‐liquid interface that provides insufficient surfactant activity. Here, we describe a strategy rationally regulate activity platelet membrane vesicles by adjusting ratio proteins lipids through fusion synthetic phospholipids (i.e., liposomes). A “platesome”...
Bacillus thuringiensis (Bt) is widely used to produce biological pesticides. However, its persistence limited because of ultraviolet (UV) rays. In our previous study, we found that exogenous intermediates the urea cycle were beneficial Bt for survival under UV stress. To further explore effect on resistance mechanism Bt, rocF/argG gene, encoding arginase and argininosuccinate synthase, respectively, knocked out recovered in this study. After target genes removed, tested was inhibited varying...
To explore the acupoint selection rules of acupuncture for Alzheimer's disease (AD) in modern clinical practice by complex network technology.The relevant articles trials were retrieved from CNKI published before December 2017. Using Microsoft Excel 2010, database was established. Gephi 0.8.2 software, mode built and its topological structure analyzed.Finally, 81 eligible 114 prescriptions extracted. The constructed AD characteristics as small world effect scale-free property, crucial...
Background: Studies have found that autophagy could promote the clearance of Aβ. To and maintain occurrence in Alzheimer's disease (AD) might be a potential way to reduce neuronal loss improve learning memory AD. Objective: investigate possible mechanisms Yishen Huazhuo Decoction (YHD) against AD model. Methods: Forty 7-month-old male SAMP8 mice were randomly divided into model (P8) group YHD group, 20 each with SAMR1 as control (R1) group. All intragastrically administered for 4 weeks, at...
The increasing heavy metal pollution in the sugarcane soil along Huanjiang River was caused by leakage and spills from Pb Zn tailing dams during a flood event.A 12-month experiment conducted farmland with contaminated to evaluate potential of for remediation As, Pb, Cd, Cu, Zn.Total available concentrations soils were analyzed before after phytoremediation application.The concentration reduced compared no treatments.Elements showed low mobility, which related their total soil.Cu exhibited...
Abstract Background Fusobacterium nucleatum ( F. ) belongs to the genus Fusobacterium, which is a gram-negative obligate anaerobic bacterium. Bacteremia associated with serious complication, not common in clinic, especially when it combined other intracranial pathogenic microorganism infection. We reported for first time case of bacteremia Porphyromonas gingivalis P. and herpes simplex virus type 1 HSV-1 Case presentation A 60-year-old woman was admitted our hospital headache week that...
This article, based on an embodied cognitive perspective, focuses the design of outdoor recreation spaces for children in preoperational stage. It explores theory and specific requirements children's spaces, highlighting suitability cognition current needs. By analyzing characteristics stage reviewing relevant research, this study proposes elements cognition. Six strategies are presented, including participation, sensory experiences, spatial layout, natural elements, image symbol...
Chaetomorpha valida is a filamentous green tide algae that causes serious damage to aquatic ecosystems and aquaculture. Vibrio alginolyticus Y20 new type of algicidal bacterium has effect on Ch. valida. This study investigated the physiological molecular responses exposure V. Y20. The inhibitory was concentration-dependent, with lowest concentration being 3 × 105 cfu mL-1. Microscopic results revealed under influence Y20, experienced severe morphological damage, dispersion intracellular...
Background: Aging is the primary risk factor for onset of Alzheimer’s disease (AD). Inflammatory aging a major feature in process aging, and chronic neuroinflammation caused by inflammatory closely related to AD. As main participant neuroinflammation, polarization microglia (MG) could influence development neuroinflammation. Preliminary studies have found that Yishen Huazhuo Decoction (YHD) promote removal Aβ1-42 regulating autophagy improve memory loss SAMP8 mice. However, it still unclear...