A5059368273- Parasitic Infections and Diagnostics
- Health and Lifestyle Studies
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Retinal Diseases and Treatments
- Metabolomics and Mass Spectrometry Studies
- Acute Lymphoblastic Leukemia research
- Diabetes and associated disorders
- Cancer Immunotherapy and Biomarkers
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Nuts composition and effects
- Computational Drug Discovery Methods
- Pharmacogenetics and Drug Metabolism
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Coccidia and coccidiosis research
- Pancreatic and Hepatic Oncology Research
- CAR-T cell therapy research
- Veterinary medicine and infectious diseases
- Bioinformatics and Genomic Networks
- Parasites and Host Interactions
- Ferroptosis and cancer prognosis
- Childhood Cancer Survivors' Quality of Life
King Abdulaziz University
2021-2025
National Guard Health Affairs
2024
King Saud bin Abdulaziz University for Health Sciences
2024
Umm al-Qura University
2024
King Abdulaziz Medical City
2024
University of Jeddah
2024
King Abdullah International Medical Research Center
2024
JAK2 is a non-receptor tyrosine kinase that regulates cellular proliferation and growth. frequently the target of mutations in cancer, particularly myeloid leukemia, lymphoid myeloproliferative neoplasms (MPN), because its important function hematopoiesis. There lot work being done to discover therapeutic medications for affected people these are widespread among various ethnicities throughout world. Constitutive activation most frequent outcome mutations, whether they point, deletion, or...
Globally, type 2 diabetes mellitus (T2DM) is an epidemic medical problem that adversely affect the patient’s functional capacity and quality of life (QoL). This study designed to examine effects weight reduction program on biochemical parameters for obese T2DM patients. Eighty subjects with (48 males 32 females), range their body mass index (BMI) was 30 34 Kg/m2. Smoking, pregnancy, heart, kidney, hepatic respiratory failure were main exclusion criteria. Participants randomly assigned into...
It has recently been estimated that non-alcoholic steatohepatitis (NASH) affects 10–24% of people worldwide. Prior research shown individuals with chronic NASH frequently have inadequate immune system response. Nonetheless, for patients, obesity is strongly linked to compromised function. The purpose this study was determine how obese patients’ responses a weight-loss program were affected by specific immunological characteristics. In study, 80 Saudi patients body mass indices (BMIs) ranging...
Abstract Breast cancer is caused by aberrant breast cells that proliferate and develop into tumors. Tumors have the potential to spread throughout body become lethal if ignored. Metastasis process which invasive tumors move neighboring lymph nodes or other organs. can be perhaps fatal. The objective of our study was elucidate molecular mechanisms underlying transition Ductal Carcinoma In Situ (DCIS) Invasive (IDC), with a particular focus on hub genes therapeutic agents. Using Weighted Gene...
Combining immune checkpoint inhibitors, specifically nivolumab (anti-PD-1) and ipilimumab (anti-CTLA-4), holds substantial promise in revolutionizing cancer treatment. This review explores the transformative impact of these combinations, emphasizing their potential for enhancing therapeutic outcomes across various cancers. Immune proteins, such as PD1 CTLA4, play a pivotal role modulating responses. Blocking checkpoints unleashes anticancer activity, synergy observed when combining multiple...
Background and Objectives. The enzyme methionine synthase reductase is involved in cellular methylation reactions, DNA synthesis, epigenetic processes. It encoded by the MTRR gene, which garnered a lot of attention current medical genetics research. This study was conducted to association between (A66G) polymorphism risk developing acute lymphoblastic leukemia among Sudanese patients. Materials Methods. case-control 150 patients with (ALL) healthy participants as control group were enrolled....
Introduction: To date few studies have investigated the correlation between inflammatory markers and lipoproteins in serum of age-related macular degeneration (AMD) patients, often reporting conflicting findings. This study aimed to investigate lipid analytes C-reactive protein (CRP) levels individuals diagnosed with dry AMD. Methods: A standard clinical panel (total cholesterol, triglycerides, high-density lipoprotein [HDL], low-density lipoproteins) CRP laboratory results were...
Background Cryptosporidiosis is an opportunistic parasitic disease widely distributed worldwide. Although Cryptosporidium sp. causes asymptomatic infection in healthy people, it may lead to severe illness immunocompromised individuals. Limited effective therapeutic alternatives are available against cryptosporidiosis this category of patients. So, there urgent need for cryptosporidiosis. Recently, the potential uses Eugenol (EUG) have been considered a promising novel treatment bacterial and...
Kola nut extracts have recently been reported to contain chemopreventive compounds providing several pharmacological benefits. This study investigated extracts' anti-cancer activity on human immortalized myelogenous leukemia cell line K562 through apoptosis and cycle arrest. Fresh nuts were prepared as powder dissolved in DMSO. Different concentrations (50, 100, 150, 200, 250 μg/ml) of working solutions prepared. The cells treated with the different extract or vehicle control (10% DMSO)...