A5053997008- Iron Metabolism and Disorders
- Pediatric Urology and Nephrology Studies
- Complement system in diseases
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
Hospital Universitário de Santa Maria
2019-2025
Universidade Federal de Mato Grosso do Sul
2025
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of thrombotic microangiopathy (TMA) caused by the dysregulation alternative complement pathway. The diagnosis TMA made clinically triad: microangiopathic anemia, thrombocytopenia, and organ damage (mainly acute kidney injury). heterogeneity clinical manifestation lack gold standard diagnostic test makes precise aHUS challenging process that may impact patient management. Until one decade ago, there was no specific treatment for...
Objective To develop a clinical score for the early identification of chronic kidney disease (CKD) in children and adolescents. The diagnosis CKD childhood allows adoption measures to slow progression disease, thereby reducing morbidity mortality. Nevertheless, is often made too late proper patient management. Study design We preformed case-control study multicenter Brazilian sample 752 pediatric patients; cases (n = 376) were patients with median estimated GFR 37 (IQR 22 57) ml/min/1.73 m2....
Introdução: A síndrome hemolítico-urêmica atípica (SHUa) é uma condição rara de microangiopatia trombótica, com acometimento multissistêmico e manifesta-se clinicamente pela tríade anemia hemolítica microangiopática não imune, trombocitopenia injúria renal. O prognóstico, nestes casos, desfavorável devido a elevada taxa morbidade mortalidade na fase aguda, além do risco evolução para doença renal crônica terminal em cerca 50% dos casos. objetivo deste trabalho relatar o caso paciente...