A5112840239- Probiotics and Fermented Foods
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Immune Response and Inflammation
- Supercapacitor Materials and Fabrication
- Transgenic Plants and Applications
- Nanoplatforms for cancer theranostics
- Luminescence Properties of Advanced Materials
- Gut microbiota and health
- Luminescence and Fluorescent Materials
- Pediatric health and respiratory diseases
- Viral gastroenteritis research and epidemiology
- Advanced battery technologies research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Advancements in Battery Materials
University of South China
2020-2024
Northwest Normal University
2019
Abstract Aims To evaluate the protective effect of intestinal supplementation with Lacticaseibacillus casei CNRZ1874 on inflammatory response induced by Mycoplasma pneumoniae in C57BL/6 J mice, and provide a potential strategy for alleviating M. pneumonia. Methods results mice were gavaged L. or PBS 7 consecutive days, then infected day 8. Treatment significantly reduced loads lungs alleviated lung inflammation 3 10 after pathogen infection. Importantly, oral administration promoted M1...
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in which neutrophils play critical role. Immune-responsive gene 1 (IRG1), responsible for itaconate production, has emerged as an important regulator inflammation and infection, but its role during M . infection remains unknown. Here, we reveal that endogenous pro-inflammatory metabolite infection. Irg1 knockout (KO) mice had lower levels bacterial burden, lactate dehydrogenase (LDH), cytokines compared with wild-type...
Mycoplasma pneumoniae represents one of the significant etiologies community-acquired pneumonia in pediatric patients. However, clinical treatment M. infection children has encountered challenges due to escalating resistance quinolones. Numerous studies have highlighted potential probiotic lactobacillus administration boosting immune responses bacterial and viral respiratory infections. In this study, protective efficacy pre-oral Lacticaseibacillus rhamnosus GG (LGG), Limosilactobacillus...