A5010475081- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Biomarkers in Disease Mechanisms
- Advanced X-ray and CT Imaging
- Blood transfusion and management
- Venous Thromboembolism Diagnosis and Management
- Bone fractures and treatments
- Medical Imaging and Analysis
- Cardiac Valve Diseases and Treatments
- Surgical site infection prevention
- Bone Metabolism and Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Shoulder and Clavicle Injuries
- Atrial Fibrillation Management and Outcomes
- Mesenchymal stem cell research
- Heterotopic Ossification and Related Conditions
- Environmental and Sediment Control
- Bacterial biofilms and quorum sensing
- Hemostasis and retained surgical items
- Case Reports on Hematomas
- Sport Psychology and Performance
IRCCS Humanitas Research Hospital
2015-2025
Fondazione Humanitas per la Ricerca
2009-2025
University of Genoa
2022-2024
CIMA Research Foundation
2022-2024
Humanitas University
2014-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2024
International Flame Research Foundation
2022-2023
Ospedale Santa Corona
2006-2018
University of Naples Federico II
2006
West Virginia University
2002
Over the last two decades, several conservative femoral prostheses have been designed. The goals of stems include: spearing trochanteric bone stock; a more physiological loading in proximal femur reducing risk stress shielding; and to avoid long stem into diaphysis preventing impingement with cortex thigh pain.All designed be less invasive than conventional uncemented are commonly named 'short stems'. However, this term is misleading because it refers heterogeneous group deeply different...
Bone remodelling around a stem is an unavoidable long-term physiological process highly related to implant design. For some predisposed patients, it can lead periprosthetic bone loss secondary severe stress-shielding, which thought be detrimental by contributing late loosening, fracture, and thus rendering revision surgery more complicated. However, these concerns remain theoretical, since loosening has yet documented among ingrowth cementless stems demonstrating associated with...
Missed torsional femur deformities may contribute to reasons for failure after open and more likely arthroscopic hip preservation surgery. A number of surgical approaches have been described addressing torsion abnormalities. This report describes a subtrochanteric osteotomy technique in consecutive series patients with complex pathologies, which intertrochanteric is not suitable precise derotation required. Subtrochanteric was performed, always combination dislocation, accordance the...
Controversies exist regarding the best treatment for slipped capital femoral epiphysis (SCFE). Subcapital anatomical reorientation of by surgical dislocation and a retinacular soft tissue flap has been described recently as an effective approach. We evaluated clinical radiographic efficacy this technique compared these to published results. A series 20 SCFE (18 stable, 2 unstable) treated subcapital re-orientation through hip extended was reviewed retrospectively. Preoperatively at most...
Background: Total hip arthroplasty (THA) follow-up is conventionally conducted with serial X-ray imaging in order to ensure the early identification of implant failure. The purpose this study develop an automated radiographic failure detection system. Methods: 630 patients THA were included study, two thirds which needed total or partial revision for prosthetic loosening. analysis based on one antero-posterior and lateral view obtained from each patient during routine post-surgery follow-up....
Abstract Autosomal recessive osteopetrosis (ARO) is a rare genetic bone disease with genotypic and phenotypic heterogeneity, sometimes translating into delayed diagnosis treatment. In particular, cases of intermediate severity often constitute diagnostic challenge represent good candidates for exome sequencing. Here, we describe the tortuous path to identification molecular defect in two siblings, which diagnosed early childhood followed milder course, allowing them reach adult age...
Background: Periprosthetic joint infection (PJI) remains a significant and complex complication following total hip knee arthroplasty. This study aims to design, validate, assess machine learning (ML) model for predicting the likelihood of PJI in individuals undergoing revision arthroplasty procedures. Methods: A retrospective analysis was conducted on patients who underwent or between 1 January 2015 31 March 2021. Data were collected from preoperative clinical histories, laboratory results,...
Background/Objectives: A missed periprosthetic joint infection (PJI) diagnosis can lead to implant failure. However, date, no gold standard for PJI exists, although several classification scores have been developed in the past years. The primary objective of study was evaluation inter-rater reliability between five systems when defining a patient who is infected. Two secondary outcomes were further examined: assessed by comparing classifications pairs, and each system within subcategories...
The relevance of prosthetic component orientation to prevent dislocation and impingement following total hip arthroplasty (THA) has been widely accepted. We investigated the use a non-computer-based surgery address reciprocal acetabular femoral components.In femur first technique, cup is positioned relative stem. When definitive antetorsion fixed, in compliant anteversion Clinical radiographic assessments were performed before 3 months after THA. Radiographic assessment was standing position...
Objective To investigate the effects of Action Observation and Motor Imagery administered day before surgery on functional recovery in patients after total hip arthroplasty. Design Randomised controlled trial. Setting Humanitas Clinical Research Center, Milan, Italy Participants Eighty inpatients with end-stage osteoarthritis undergoing Interventions All followed a standardized postoperative rehabilitation program. Experimental group (AO + MI) performed two 12-minute sessions preoperative...
The incidence of periprosthetic joint infections (PJIs) is ~2% total procedures and it expected to rise due an ageing population. Despite the large burden PJI has on both individual society, immune response most commonly isolated pathogens, i.e., Staphylococcus aureus epidermidis, remains incompletely understood. In this work, we integrate analysis synovial fluids from patients undergoing hip knee replacement surgery with in-vitro experimental data obtained using a newly developed platform,...