Yang Zhang

ORCID: 0009-0004-4322-1329
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About
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Research Areas
  • Protein Hydrolysis and Bioactive Peptides
  • Biochemical and Structural Characterization
  • Nutrition and Health in Aging
  • GDF15 and Related Biomarkers
  • Frailty in Older Adults
  • Spinal Fractures and Fixation Techniques
  • Medical Imaging and Analysis
  • Scoliosis diagnosis and treatment
  • Antimicrobial Peptides and Activities

Southern Medical University
2024

Owing to their limited accuracy and narrow applicability, current antimicrobial peptide (AMP) prediction models face obstacles in industrial application. To address these limitations, we developed improved an AMP model using Comparing Optimizing Multiple DEep Learning (COMDEL) algorithms, coupled with high-throughput screening method, finally reaching of 94.8% test 88% experiment verification, surpassing other state-of-the-art models. In conjunction COMDEL, employed the phage-assisted...

10.1016/j.apsb.2024.05.003 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2024-05-10

Abstract To screen characteristic genes related to sarcopenia by bioinformatics and machine learning, verify the accuracy of in diagnosis sarcopenia. Download myopia-related data sets from geo public database, find differential through R language limma package after merging, STRING database build protein interaction network, do Go analysis GSEA understand functions molecular signal pathways that may be affected genes. Further LASSO SVM-RFE algorithms, make ROC curve genes, obtain AUC value....

10.1186/s40001-023-01603-8 article EN cc-by European journal of medical research 2024-01-16
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