A5060664045- Genetic factors in colorectal cancer
- Advanced Breast Cancer Therapies
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Lung Cancer Research Studies
- Colorectal Cancer Screening and Detection
- Gestational Trophoblastic Disease Studies
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- Esophageal Cancer Research and Treatment
- Anesthesia and Sedative Agents
- Chronic Lymphocytic Leukemia Research
- History and advancements in chemistry
- Cancer-related cognitive impairment studies
Instituto Alexander Fleming
2022-2025
Instituto de Oncología de Rosario
2025
Background/Objectives: BRAF-mutation is a poor prognostic factor in colorectal cancer (CRC). There need for real-world data low-middle-income countries regarding clinical characteristics, outcomes, and treatment strategies. This study aims to describe progression free survival (PFS) overall (OS) the first-line setting, sequences of regimens. Methods: We retrospective analyze patients from ten oncology centers Argentina, diagnosed with BRAFV600E-mutated advanced CRC between January 2014 July...
Background/Objectives: The BRAF-mutation is a poor prognostic factor in colorectal cancer (CRC). There need for real-world data low-middle-income countries regarding clinical characteristics, outcomes, and treatment strategies. This study aims to describe progression-free survival (PFS) the first- second-line setting sequences of regimens. Methods: We retrospectively analyze patients from ten oncology centers Argentina, diagnosed with BRAFV600E-mutated advanced CRC between January 2014 July...
e21031 Background: Mentorship is a valuable aspect of professional development in oncology. It has been associated with an increase job satisfaction, self-confidence and career success, while contributing to the reduction burnout. To date, there are no published examples implementation mentorship programs oncology Latin America. We aimed develop evaluate pioneering program enhance training reduce burnout fellows. Methods: The Leadership Mentoring Program was developed after systematic review...
1056 Background: HER2-low expression, defined as HER2 immunohistochemistry (IHC) score of 1+ or 2+ with negative in situ hybridization assay (FISH), accounts for 50% breast cancers. There is limited and conflicting evidence regarding the efficacy cyclin-dependent kinase (CDK) 4 6 inhibitors patients ER+ tumors. This study aimed to investigate prognostic value expression ER+/HER2-negative advanced cancer treated CDK 4/6 inhibitors. Methods: We retrospectively selected consecutive plus...
Gastroesophageal cancers, are among the most prevalent cancers globally and represent third leading cause of cancer-related mortality worldwide. Surgical resection remains primary curative approach for localized locally advanced stages, but its effectiveness is limited diseases, evidenced by a low 5-year survival rate around 25%. High relapse rates post-surgery, particularly in western populations, necessitate use neoadjuvant, adjuvant, or perioperative strategies involving chemotherapy...
Introducción: El tratamiento estándar para pacientes con cáncer de mama RH+/HER2- avanzado involucra el uso un inhibidor quinasas dependientes ciclinas 4/6 (iCDK4/6), junto terapia hormonal. Se ha demostrado la eficacia ribociclib en sobrevida libre progresión y global. Objetivos: En este estudio se plantea importancia evaluar toxicidad tiempo, es decir, tiempo dedicado a atención médica, entorno del mundo real RH+/HE2- enfermedad avanzada que encuentran recibiendo ribociclib....
Objectives We aim to investigate the time toxicity of patients with gastroenteropancreatic neuroendocrine tumours treated Lutetium-177 Dotatate in a single institution. Design This is retrospective cohort study. Methods All at Alexander Fleming Institute were included. Our primary endpoint was evaluate toxicity, which accounted for every day that patient had contact any department healthcare Results included 21 metastatic disease, female sex 86%, and median age 55 (IQR 44–63). The tumour...
Introducción: El cáncer colorrectal (CCR) en adultos jóvenes es una entidad cada vez más prevalente y se estima que la próxima década 1 de 4 pacientes sea menor 50 años. En nuestro país existen pocos datos este subgrupo pacientes. Métodos: Estudio cohorte retrospectivo, atendidos nuestra institución, con CCR confirmados histológicamente, desde enero 2018 a junio 2023 menos años al momento del diagnóstico. objetivo primario fue describir las características clínico-patológicas moleculares 3...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)