A5064257214- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Biosimilars and Bioanalytical Methods
- Systemic Sclerosis and Related Diseases
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Pharmaceutical studies and practices
- Vitamin D Research Studies
- Autoimmune and Inflammatory Disorders Research
- Neuroscience of respiration and sleep
- Health and Lifestyle Studies
- SARS-CoV-2 and COVID-19 Research
- Autoimmune Bullous Skin Diseases
- Pharmaceutical Economics and Policy
- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
- Immunodeficiency and Autoimmune Disorders
- Adrenal Hormones and Disorders
- Inhalation and Respiratory Drug Delivery
- Lysosomal Storage Disorders Research
- Adipokines, Inflammation, and Metabolic Diseases
- Vasculitis and related conditions
- Muscle and Compartmental Disorders
- Poisoning and overdose treatments
- Hematopoietic Stem Cell Transplantation
Guyra Paraguay
2018-2025
Ministerio de Salud Pública y Bienestar Social
2023
Universidad Nacional de Asunción
2016-2022
Hospital de Cruces
1996-2021
BioCruces Health research Institute
2021
Hospital de Clínicas
2016-2018
Medicina
2017
University of the Basque Country
1999-2003
Badalona Serveis Assistencials
1998
Classic infantile Pompe disease (IPD) is a rare lysosomal storage disorder characterized by severe hypertrophic cardiomyopathy and profound muscle weakness. Without treatment, death occurs within the first 2 years of life. Although enzyme replacement therapy (ERT) with alglucosidase alfa has improved survival, treatment outcome not good in many cases largely dependent on age at initiation. The objective study was (a) to analyse different stages diagnosis specific initiation procedure IPD...
La vitamina D es una hormona cumple funcion en la regulacion de numerosos genes que participan proliferacion y maduracion celular. El objetivo este trabajo fue determinar prevalencia valores inadecuados esta jovenes sanos Asuncion e identificar los posibles factores riesgo asociados. Estudio observacional descriptivo basado datos clinico-epidemiologicos determinacion 25-hidroxivitamina (25-OH D) por el metodo quimioluminiscencia (CMIA). Se considero valor adecuado ≥30 ng/dl, inadecuado...
Background: Metabolic syndrome (MS) is associated with increased abdominal adipose tissue and production of inflammatory cytokines. Patients MS are at risk for developing cardiovascular disease diabetes mellitus, which among the leading causes death in chronic rheumatic diseases. Objectives: To characterize patients its association markers. Methods: Descriptive, cross sectional, prospective study, 3 Paraguayan cohorts rheumatoid arthritis (RA), systemic sclerosis (SSc) lupus erythematosus...
Introducción: La artritis reumatoide (AR) es una enfermedad inflamatoria crónica, autoinmune, sistémica. El diagnóstico temprano, la implementación de un tratamiento bajo objetivos específicos, estrictos y el desarrollo nuevos tratamientos han mejorado pronóstico los pacientes. Objetivo: Proporcionar información detallada sobre las características demográficas, clínicas terapéuticas pacientes con AR en país. Materiales Métodos: Estudio descriptivo, corte transversal, cohorte AR, tres centros...
Introducción: Existen diferencias entre pacientes con Artritis Reumatoide (AR) de inicio y establecida que pueden condicionar calidad vida el pronóstico la enfermedad.
<h3>Background</h3> Systemic Lupus Erythematosus (SLE) and rheumatoid arthritis (RA) are autoimmune diseases that mainly affect people in the reproductive stage of their life; it is interesting to investigate impact both have patient9s quality life. <h3>Objectives</h3> The main objective this study was evaluate life patients diagnosed with SLE RA using SF36 questionnaire factors influence <h3>Methods</h3> Analytical, observational cross-sectional a cohort patients. A large number clinical...
<h3>Background</h3> Patients with Rheumatoid Arthritis show an increased mortality population due predominantly to cardiovascular complications, which represent up 50% of deaths. There are CVR scales that include RA as independent risk factor. Even constantly revised and updated assessment tools such Qrisk III SCOREm, there is still a tendency underestimate the evidenced by asymptomatic atherosclerosis on ultrasound carotid vessels in patients previously classified intermediate or low...
<h3>Background</h3> BIOBADAGUAY is the Paraguayan/Uruguayan registry of adverse events in patients with inflammatory rheumatic conditions under biologic therapy (BT). The includes different diagnosis that share similar biological therapies indication. However, pathogenesis, patients' characteristics and treatment options can affect survival BT. <h3>Objectives</h3> To analyze among chronic arthritis registry. <h3>Methods</h3> Patients (CIA) such us rheumatoid (RA), spondylarthritis (SpA),...
<h3>Background</h3> BIOBADAGUAY is the Paraguayan/Uruguayan registry of adverse events (AE) in patients with inflammatory rheumatic conditions under biologic therapy (BT). <h3>Objectives</h3> Determine frequency and severity AE BT registry. <h3>Methods</h3> Prospective, observational study undetermined length to verify efficacy, safety, survival BT. The methodology applied available at https://biobadaguay.ser.es. For present epidemiological clinical variables, BT, type, were analyzed....
<h3>Background</h3> In February 2021, the first doses of COVID-19 vaccines were received in Paraguay, and rheumatic patients preferred population to get these vaccines. Up December 2022 vaccination coverage Paraguay was 59.4%, with at least one vaccine dose. 52.4% accessed primary scheme (two doses), while 28.6% had booster Only 7.1% completed immunization scheme. <h3>Objectives</h3> To describe against Paraguayan Rheumatoid Arthritis (RA). <h3>Methods</h3> Descriptive, cross sectional,...
Introducción: La vacunación en poblaciones expuestas a mayor riesgo de enfermedad grave y muerte consecuentes la infección por SARS-CoV-2, ha generado un gran impacto salud pública mundial. Indudablemente, el beneficio sido evidenciado mayormente personas con comorbilidades crónicas, donde artritis reumatoide (AR) juega rol importante. Objetivo: Analizar contra Sars-CoV-2 pacientes paraguayos AR, durante pandemia COVID-19. Métodos: Se realizó estudio multicéntrico, que se analizó...