A5058294991- Bone fractures and treatments
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- TGF-β signaling in diseases
- ATP Synthase and ATPases Research
- Knee injuries and reconstruction techniques
- Spine and Intervertebral Disc Pathology
- Chronic Disease Management Strategies
- S100 Proteins and Annexins
- Healthcare Systems and Public Health
- Orthopaedic implants and arthroplasty
- Cancer survivorship and care
Jena University Hospital
2024
LMU Klinikum
2024
Friedrich Schiller University Jena
2024
University Medical Center of the Johannes Gutenberg University Mainz
2019-2023
Johannes Gutenberg University Mainz
2019-2023
Abstract Background Palliative care (PC) contributes to improved end-of-life for patients with hematologic malignancies (HM) and solid tumors (ST) by addressing physical psychological symptoms spiritual needs. Research on PC in HM vs. ST is fragmented suggests less use. Methods We analyzed claims data of all deceased members a large German health insurance provider the year before death. First, we frequency beginning different types compared ST. Second, adjusted impact use several quality...
Background: After a trauma, exuberant tissue healing with fibrosis of the joint capsule can lead to posttraumatic stiffness (PTJS). Losartan and atorvastatin have both shown their antifibrotic effects in different organ systems. Objective: The purpose this study was evaluation influence losartan on early development contracture. In addition angles, change myofibroblast numbers distribution bone sialoprotein (BSP) were assessed. Study design methods: randomized blinded experimental 24 rats,...
The antifibrotic effect of atorvastatin has already been demonstrated in several organ systems. In the present study, a rat model was used to investigate on posttraumatic joint contracture. Forty-eight Sprague Dawley rats were equally randomized into an group and control group. After initial trauma, knee joints immobilized for intervals 2 weeks (n = 16) or 4 with subsequent remobilization another 16). Starting from day surgery, animals received either placebo daily. euthanasia at week 2, 8,...
Post-traumatic joint stiffness (PTJS) is accompanied by a multidimensional disturbance of architecture. Pharmacological approaches represent promising alternatives as the traumatic nature current therapeutic standards may lead to PTJS' progression. Losartan an auspicious candidate, it has demonstrated antifibrotic effect in other organs. Forty-eight Sprague Dawley rats were randomized into equally sized losartan or control groups. After standardized knee trauma, was immobilized for either 2...
Objectives: ICD-10-based approaches often provide the basis for retrospective estimation of potential palliative care need. Applying Murtagh et al. classification from 2014 (Murtagh classification), developed using mortality data, to administrative claims data leads inconsistencies in estimating The aim study was refine need deceased individuals with cancer and non-cancer diagnosis. Methods: A population-based comparing a new (revised by expert opinion) conducted outpatient inpatient...