A5045167165- Circular RNAs in diseases
- Nuclear Receptors and Signaling
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
Central Hospital of Zibo
2020
<p>Figures S1 to S6, Table S1, and S2</p>
<p>The information of tissue samples from 73 liver cancer patients.</p>
<p>Untargeted lipidomics analysis in Control and circEPB41(2) knockdown cells</p>
<p>List of H3K9ac Peaks in Control and circEPB41(2) Knockdown Cells</p>
<p>Overlapping Genes with Decreased H3K9ac Deposition and Down-regulated Expression upon circEPB41(2) Knockdown</p>
<p>Targeted lipidomics analysis in Control and circEPB41(2) knockdown cells</p>
<div>Abstract<p>The tumor microenvironment plays a pivotal role in the metabolic reprogramming of cancer cells. A better understanding underlying mechanisms regulating metabolism could help identify potential therapeutic targets. Here, we identified circEPB41(2) as metabolically regulated circular RNA that mediates lipid hepatocellular carcinoma (HCC). was induced response to glucose deprivation via HNRNPA1-dependent alternative splicing. Upregulation led enhanced lipogenic gene...
<p>Figures S1 to S6, Table S1, and S2</p>
<p>List of H3K9ac Peaks in Control and circEPB41(2) Knockdown Cells</p>
<p>Targeted lipidomics analysis in Control and circEPB41(2) knockdown cells</p>
<p>Overlapping Genes with Decreased H3K9ac Deposition and Down-regulated Expression upon circEPB41(2) Knockdown</p>
<p>The information of tissue samples from 73 liver cancer patients.</p>
<p>Untargeted lipidomics analysis in Control and circEPB41(2) knockdown cells</p>
Gallbladder cancer (GBC) is a malignant tumors that develops insidiously and rapidly. In this work, we explored the function of long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) in modulating GBC development. PVT1 miR-30d-5p expression were detected by real-time fluorescent quantitative polymerase chain reaction (qRT-PCR). The relationship was analyzed Dual luciferase activity Spearman correlation analysis. effect on progression cell counting kit-8 (CCK-8) Transwell...
Abstract The tumor microenvironment plays a pivotal role in the metabolic reprogramming of cancer cells. A better understanding underlying mechanisms regulating metabolism could help identify potential therapeutic targets. Here, we identified circEPB41(2) as metabolically regulated circular RNA that mediates lipid hepatocellular carcinoma (HCC). CircEPB41(2) was induced response to glucose deprivation via HNRNPA1-dependent alternative splicing. Upregulation led enhanced lipogenic gene...