Wenlu Hang

ORCID: 0009-0004-5997-9281
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Research Areas
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Hydrogen's biological and therapeutic effects
  • Pulmonary Hypertension Research and Treatments
  • Occupational and environmental lung diseases
  • Occupational exposure and asthma
  • Legionella and Acanthamoeba research
  • Bone Tissue Engineering Materials
  • 3D Printing in Biomedical Research
  • Phytochemicals and Antioxidant Activities
  • Additive Manufacturing and 3D Printing Technologies
  • Systemic Sclerosis and Related Diseases
  • Polymer Nanocomposites and Properties
  • Indoor Air Quality and Microbial Exposure
  • Orthopaedic implants and arthroplasty
  • Cancer-related molecular mechanisms research
  • Tribology and Wear Analysis
  • RNA modifications and cancer
  • Sarcoidosis and Beryllium Toxicity Research
  • Ferroptosis and cancer prognosis
  • Asthma and respiratory diseases
  • Bioactive Compounds in Plants
  • Circular RNAs in diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation

Xuzhou Medical College
2021-2025

Nanjing University of Chinese Medicine
2021

Second Affiliated Hospital of Xuzhou Medical College
2021

Introduction Lung adenocarcinoma (LUAD) is a prevalent form of lung cancer originating from glandular cells with low survival rates despite recent therapeutic advances due to its diverse and complex nature. Recent evidence suggests link between ferroptosis the effectiveness anti-PD-L1 therapy, potential synergistic effects. Methods Our study comprehensively analyzed expression patterns regulators in LUAD their association prognosis PD-L1 expression. Furthermore, we identified two distinct...

10.3389/fimmu.2024.1372215 article EN cc-by Frontiers in Immunology 2024-04-09

Abstract Diseases such as injury, stenosis, and tumors of the long trachea usually require removal affected part trachea. There is an urgent need to implant tracheal stents substitutes in clinical practice. In this paper, Mg 2+ was first doped into hydroxyapatite (HA) matrix by hydrothermal synthesis then mixed with gelatin sodium alginate (Gel–SA) double network crosslinked hydrogel prepare magnesium (Gel–SA–MgHA) composite biomaterial ink. The stent prepared 3D bioprinting technology its...

10.1002/slct.202403228 article EN ChemistrySelect 2025-01-01

ABSTRACT In order to improve the wear and aging resistance of UHMWPE based polymer acetabular cup prosthesis, hot‐embossing method is used prepare multi‐component MWCNTs/ZnO added composite materials in this article. The research results found that diffusion characteristics additives have a significant impact on their resistance. Under condition 25% NBS, rate UMZ‐3 sample was 13.94% lower than pure U sample. Although MWCNTs can play role reducing friction certain extent, high hardness may...

10.1002/app.56893 article EN Journal of Applied Polymer Science 2025-02-18

Background: Nintedanib and pirfenidone are preferred pharmacological therapies for patients with idiopathic pulmonary fibrosis (IPF). However, evidence favoring antifibrotic therapy in non-IPF fibrosing interstitial lung diseases (ILD) is limited. Objective: To investigate the effects of on disease progression, all-cause mortality, acute exacerbation (AE) risk ILDs. Design: Meta-analysis. Data sources methods: Electronic databases were searched articles published before 28 February 2023....

10.1177/17534666241232561 article EN cc-by-nc Therapeutic Advances in Respiratory Disease 2024-01-01

The incidence of pulmonary fibrosis (PF), a progressively fatal disease, has increased in recent years. However, there are no effective medicines available. Previous results have shown that sinensetin probably some curative effects on PF. Therefore, this paper aims to predict the targets using network pharmacology method and confirm its functional PF mouse model. First, analysis showed 105 targets, 1,698 gene closely relate intersection produced 52 for treatment with sinensetin. PPIs...

10.3389/fphar.2021.693061 article EN cc-by Frontiers in Pharmacology 2021-06-18

Abstract Background: Non-small cell lung cancer (NSCLC) is a disease with quite grave prognosis. This study explored the diagnostic efficiency of miR-126-5p and miR-34c-3p in serum extracellular vesicles (EVs) NSCLC patients. Methods: Serum EVs were extracted from patients healthy people verified. The expression tested. Correlation diagnosis, prognosis pathological characteristics (age, gender, tumor size, clinical stage, lymph node metastasis) was analyzed. downstream targets predicted...

10.21203/rs.3.rs-861245/v1 preprint EN cc-by Research Square (Research Square) 2021-09-07

Background: Silicosis is a public health issue in developing countries for long and cannot be completely cured. Objective: To study the changes of ion content with TNF-α TGF-β expression alveolar lavage fluid (BALF) at different time points rats exposed to silica investigate their correlation pulmonary fibrosis. Methods: 42 were randomly divided into control group ( n = 12) exposure 30). Tissues right lower lungs collected fixed further Hematoxylin-eosin (HE) Masson staining. We BALF examine...

10.4103/ijpm.ijpm_433_20 article EN cc-by-nc-sa Indian Journal of Pathology and Microbiology 2021-10-01

Objective To explore the effect of knowledge-attitude-belief-practice (KABP) model in compliance with treatment by noninvasive ventilator patients type Ⅱ respiratory failure. Methods 40 failure were randomly divided into group (n=20) and control (n=20). The conventional health education program was administered to KABP applied group.The compared these two groups. Results The higher than (P<0.05). Conclusions Compared routine education, is helpful for change their attitudes...

10.3760/cma.j.issn.1673-436x.2017.24.009 article EN Chinese Journal of Asthma 2017-12-20
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