- Bacteriophages and microbial interactions
- Microbial Natural Products and Biosynthesis
- Insect Utilization and Effects
- Chemical synthesis and alkaloids
- Biochemical and Molecular Research
- Probiotics and Fermented Foods
- Phytochemistry and Bioactivity Studies
- Animal and Plant Science Education
- Microbial Metabolic Engineering and Bioproduction
- Microbial metabolism and enzyme function
- Gut microbiota and health
- Photosynthetic Processes and Mechanisms
Technische Universität Dresden
2021-2025
Abstract The hyphal nature of filamentous streptomycetes poses unique challenges to their multicellular lifestyle, since it requires organizing cellular functions at the scale hundreds micrometers length. Streptomycetes exhibit a strong and patchy autofluorescence so far unknown origin in hyphae that – as we demonstrate is natural property actinobacteria. foci are dynamic evenly distributed throughout hyphae, including tips, where they cell membrane-associated. Here, resolved high...
Human health is greatly influenced by the gut microbiota and imbalance can lead to development of diseases. It widely acknowledged that interaction bacteria within competitive ecosystems their specialized metabolites, which act, e.g., as antibacterials or siderophores. However, our understanding occurrence impact such natural products in human microbiome remains very limited. As arylthiazole siderophores are an emerging family growth-promoting molecules pathogenic bacteria, we analyzed a...
Human health is greatly influenced by the gut microbiota and imbalance can lead to development of diseases. It widely acknowledged that interaction bacteria within competitive ecosystems their specialized metabolites, which act, e.g., as antibacterials or siderophores. However, our understanding occurrence impact such natural products in human microbiome remains very limited. As arylthiazole siderophores are an emerging family growth-promoting molecules pathogenic bacteria, we analyzed a...
With the growing importance of black soldier fly (Hermetia illucens) for both sustainable food production and waste management as well science, a great demand understanding its immune system arises. Here, we present first description circulating larval hemocytes with special emphasis on uptake microorganisms distinguishing hemocyte types. histological, zymographic, cytometric methods set binding lectins antibodies, H. illucens are identified plasmatocytes, crystal cells, putative...
The ambigols are cyanobacterial natural products characterized by three polychlorinated aromatic building blocks connected biaryl and ether bridges. All known to date possess promising biological activities. Most significantly, ambigol A was reported have antibacterial activity against Gram-positive bacteria, such as Bacillus megaterium B. subtilis. We established a diverse compound library for in-depth evaluation on our previous bio- total synthetic research this product family. To explore...