A5017838174- Gut microbiota and health
- Oral microbiology and periodontitis research
- Clostridium difficile and Clostridium perfringens research
- Parasites and Host Interactions
- Oral Health Pathology and Treatment
- Pneumonia and Respiratory Infections
University of Ghana
2023-2024
Noguchi Memorial Institute for Medical Research
2022-2024
University of Illinois Urbana-Champaign
2022
Pan African Institute for Development
2022
Institute for Basic Science
2022
Pan-Atlantic University
2022
Yale University
2022
Abstract Microbes play a key role in human gut homeostasis, metabolic, immunologic and physiopathology of the body. A longitudinal study conducted during 2018–2021 Kintampo North Municipality Ghana demonstrated low hookworm infection cure rates following treatment with single dose 400 mg albendazole some communities. To investigate associations between microbiome, we examined stool samples from consented participants who were either cured or remained infected after treatment. At each time...
In this study, we sought to identify key microbial taxa associated with human gut dysbiosis during S. mansoni infection and whether the changes are linked intensity of helminth infection. Stool samples were obtained from 20 persons infected schistosomiasis an equal number uninfected endemic rural community in Ghana. Infection was scored as egg count per gram (EPG) using Kato-Katz method. Positive stool further stratified low-moderate (<400 EPG, n=15) high (>400 n=5) burden. The...
Abstract Background : Microbiome dysbiosis is associated with various diseases, including COVID-19. The association of the oral microbiome SARS-CoV-2 infections and disease progression has been documented in European, Asian, American populations but not Africa. Methods We conducted a study Ghana to evaluate compare naso-oropharyngeal SARS-CoV-2-infected noninfected persons before after vaccination. 16S rDNA was sequenced analysed from DNA extracted swabs consenting participants. Results...
Abstract Microbes play an important role in human gut homeostasis, metabolic, immunologic and physiopathology of the body. A longitudinal study conducted during 2018–2021 Kintampo North Municipality Ghana demonstrated low hookworm infection cure rates following treatment with a single dose 400 mg albendazole some communities. To investigate associations between microbiome, we examined faecal samples from consented participants who were either cured or remained infected after treatment. At...