A5103162621- Telomeres, Telomerase, and Senescence
- RNA modifications and cancer
- Acoustic Wave Resonator Technologies
- Cancer, Hypoxia, and Metabolism
- Cancer Cells and Metastasis
- Cancer Research and Treatments
- Cancer-related molecular mechanisms research
- Nanocluster Synthesis and Applications
- Congenital Ear and Nasal Anomalies
- Cancer Diagnosis and Treatment
- Metal and Thin Film Mechanics
- Advanced Polymer Synthesis and Characterization
- Eicosanoids and Hypertension Pharmacology
- Carbon and Quantum Dots Applications
- Magnetic Properties and Synthesis of Ferrites
- Advanced Biosensing Techniques and Applications
- Disaster Management and Resilience
- Cell Image Analysis Techniques
- Metastasis and carcinoma case studies
- Cell death mechanisms and regulation
- Climate Change, Adaptation, Migration
- Craniofacial Disorders and Treatments
- Advanced NMR Techniques and Applications
- Bone Tumor Diagnosis and Treatments
- Oral Health Pathology and Treatment
Shandong First Medical University
2021-2024
Longdong University
2024
Shandong Provincial Hospital
2015-2024
Micron (United States)
2024
University of Michigan
2024
Chongqing University
2024
Hebei University of Science and Technology
2021
Tianjin University
2021
Shandong University
2010-2019
Hospital of Stomatology, Sun Yat-sen University
2015
Head and neck squamous cell carcinoma (HNSCC) is the six leading cancer by incidence worldwide. The 5-year survival rate of HNSCC patients remains less than 65% due to lack symptoms in early stage. Hence, biomarkers which can improve detection should clinical outcome. Gene expression profiles (GSE6631, GSE58911) Cancer Genome Atlas (TCGA) data were used for integrated bioinformatics analysis; differentially expressed genes (DEGs) then subjected functional pathway enrichment analysis,...
Oral microbiota dysbiosis is associated with the occurrence and progression of oral cancer. To investigate association between risk squamous cell carcinoma (OSCC), we identified microbial composition paired tumor (TT)/normal paracancerous tissues (NPT) saliva (TS) samples in OSCC patients through 16S rRNA gene sequencing. A total 22 phyla, 321 genera, 869 species were samples. Paired comparisons revealed significant differences TT, NPT, TS groups, genus Filifactor significantly enriched TT....
Tongue squamous cell carcinoma (TSCC) is highly malignant and poorly differentiated, resulting in a high frequency of local recurrence distant metastases. Sox2 (Sry‑box2), an important factor embryonic development differentiation, has been shown to associate with phenotypes epithelial‑mesenchymal transition (EMT) progression numerous types human tumors. However, the clinical relevance molecular mechanisms TSCC remain unclear. In present study, expression levels were assessed 61 pairs samples...
Magnetic polymers show great potential in biomedical, electronic devices and magnetic responsive materials. The structure property relationship are very important design of organic polymers. In this work,...
In recent years, researchers have found the critical role of telomerase in cellular transformation, proliferation, stemness and cell survival. High levels reverse transcriptase (TERT) expression activation been reported most cancer cells. Moreover, overexpression human TERT (hTERT) is to be correlated with advanced invasive stage tumor progression poor prognosis. Epithelial-mesenchymal transition (EMT), characterized by loss cell-cell contact epithelial cells acquisition migratory motile...
Organic magnets are promising in quantum computers, spintronic devices, and information storages for their excellent processing smart design abilities, resulting from the organic part. However, part shields magnetic centers to weaken interaction. In this work, π–π stacking planar pyrene groups introduced into cations of a ionic liquid (NBPBI[FeCl4]) poly(ionic liquid) (PNBPBI[FeCl4]) with FeCl4– as anions. By introducing groups, shortest distance between neighboring units is within 4 Å. The...
// Tengda Zhao 1, 2 , Fengchun Hu 3 Xingguang Liu 1 Qian Tao Department of Oral and Maxillofacial Surgery, Guanghua School Stomatology, Hospital Sun Yat-sen University, Guangdong Provincial Key Laboratory Guangzhou, Guangdong, China Affiliated to Shandong Jinan, Shandong, The First Guangzhou University Chinese Medicine, Correspondence to: Tao, e-mail: taoqian@mail.sysu.edu.cn Keywords: TERT, HNSCC, AKT, ERK, chemosensitivity Received: April 10, 2015 Accepted: October 06, Published: 16,...
Abstract There is increasing evidence that dysregulated long non-coding RNA (lncRNA) implicated in tumorigenesis and progression. We aim to explore the role of lncRNA MIR600HG glycometabolism cisplatin (DDP) resistance oral squamous cell carcinoma (OSCC) cells via regulating microRNA-125a-5p (miR-125a-5p) RING finger 44 (RNF44). Expression MIR600HG, miR-125a-5p, RNF44 OSCC clinical samples, lines, DDP-resistant (SCC-9/DDP) was determined. In SCC-9 cells, proliferation, IC 50 value DDP,...
Main observation and conclusion Ring‐opening metathesis polymerization (ROMP) is a powerful toolbox in preparation of bottlebrush polymers for its high activity. However, the ROMP macromonomers with repeating tertiary amine groups, example, poly(2‐(dimethylamino)ethyl methacrylate) (PDMAEMA), inhibited due to coordination nitrogen atom ruthenium center ([Ru]) third generation Grubbs catalyst (G3). In this work, norbornenyl functionalized polystyrene‐block‐PDMAEMA (NB‐PS‐ b ‐PDMAEMA)...
The median cleft of the mandible and lower lip is an extremely rare congenital maxillofacial deformity, therapeutic options are controversial. To evaluate clinical characteristics identify a better choice treatment modes used among us others, we reviewed 34 relevant literature herein describe 17-year follow-up case with lip. Based on our good functional aesthetical outcomes, propose prospective treatment: Patients Tessier 30 associated could undergo mandibular repair after puberty in...
With the rapid development of 5G and MicroElectro-Mechanical System (MEMS) technology, piezoelectric film bulk acoustic resonators (FBARs) have gradually become one hotspots Radio Frequency (RF) filters. In this paper, electrical impedance model FBARs was derived based on wave transmission characteristics in thin film, traditional one-dimensional mason improved. The finite element simulation used to validate modified model. ADS software study influence thickness passivating (PAS-PZ) layer...
To bolster ecological conservation efforts and foster human well-being, the Chinese government has implemented disaster resettlement program. Rural households encounter various environmental social challenges regarding resettlement. One of priorities in China is to implement reforms mitigate losses improve livelihoods households. The research on livelihood adaptive capacity their framework provides a new perspective for survey population. This article assesses Household Livelihood Adaptive...