Chennianci Zhu

ORCID: 0009-0004-7439-8194
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Nanoparticles: synthesis and applications
  • Gastrointestinal disorders and treatments
  • Quantum Dots Synthesis And Properties
  • Bacterial biofilms and quorum sensing
  • Gastrointestinal Tumor Research and Treatment
  • Transgenic Plants and Applications
  • Gastric Cancer Management and Outcomes
  • Plant tissue culture and regeneration

Zhejiang Sci-Tech University
2019-2021

Abstract AgNPs are nanomaterials with many potential biomedical applications. In this study, the two novel yeast strains HX-YS and LPP-12Y capable of producing biological silver nanoparticles were isolated. Sequencing ribosomal DNA-ITS fragments, as well partial D1/D2 regions 26S rDNA indicated that related to species from genus Metschnikowia . The BioAgNPs produced by at pH 5.0–6.0 26 °C ranged in size 50 500 nm. antibacterial activities against five pathogenic bacteria determined. highest...

10.1038/s41598-021-95262-6 article EN cc-by Scientific Reports 2021-08-04

Abstract AgNPs is nanomaterials with many potential biomedical applications. In this study, two novel yeast strains named as HX-YS and LPP-12Y capable of producing biological silver nanoparticles were isolated. Based on sequencing ribosomal DNA-ITS fragments, well partial D1/D2 regions 26S rDNA be similar genus Metschnikowia . The BioAgNPs produced by at pH 5.0 - 6.0 26℃ ranged in size from 50 to 500 nm. antibacterial activities against five pathogenic bacteria determined. highest effect was...

10.21203/rs.3.rs-402996/v1 preprint EN cc-by Research Square (Research Square) 2021-04-14

Abstract Background Most gastrointestinal stromal tumours (GIST) are driven by activating oncogenic mutations of KIT/PDGFRA, which provide a compelling therapeutic target. Our previous studies showed that CDC37, regulated casein kinase 2 (CK2), is crucial HSP90 cofactor for KIT function and promising more selective target in GIST. Methods Biologic mechanisms CK2-mediated CDC37 regulation were assessed GISTs immunoblotting, immunoprecipitations, knockdown inactivation assays. The effects...

10.1038/s41416-019-0657-5 article EN cc-by British Journal of Cancer 2019-11-28
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