A5014774535- Hemoglobinopathies and Related Disorders
- FOXO transcription factor regulation
- Iron Metabolism and Disorders
- Neonatal Health and Biochemistry
- Blood groups and transfusion
- Heme Oxygenase-1 and Carbon Monoxide
- Muscle Physiology and Disorders
- Natural Antidiabetic Agents Studies
- Bioactive natural compounds
- Sirtuins and Resveratrol in Medicine
- Erythrocyte Function and Pathophysiology
- Phytochemicals and Antioxidant Activities
- Adipose Tissue and Metabolism
Universidade Federal de Pernambuco
2017-2023
Fundação de Amparo à Pesquisa do Estado de São Paulo
2022
Universidade Estadual de Campinas (UNICAMP)
2018-2022
Morus nigra has been used popularly for several proposes, including diabetic. In an attempt to support medicinal value, the acute hypoglycemic, hypolipidemic, and antioxidant effects of ethanolic extract (EEMn 200 or 400 mg/kg b.w.) were evaluated in normal alloxan-induced diabetic treated 14 days. Serum biochemical analysis performed at end experiment. Oral glucose tolerance test was 10th 15th Chromatographic by HPLC-DAD EEMn performed. Insulin as positive control glycemic metabolism well...
Although there are reports that polyphenol resveratrol (Rsv) may cause muscle hypertrophy in basal conditions and attenuate wasting catabolic situations, its mechanism of action is still unclear. Our study evaluated the ex vivo effects Rsv on protein metabolism intracellular signaling innervated (sham-operated; Sham) 3-day sciatic denervated (Den) rat skeletal muscles. (10-4 M) reduced total proteolysis (40%) sham Den increased (~40%) muscle, which was accompanied by an increase activities...