Liangying Zheng

ORCID: 0009-0004-8790-4295
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About
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Research Areas
  • Immune cells in cancer
  • Glioma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nuclear Receptors and Signaling
  • Ferroptosis and cancer prognosis

Southern Medical University
2023

Guangdong Provincial People's Hospital
2023

Guangdong Academy of Medical Sciences
2023

Affiliated Eye Hospital of Wenzhou Medical College
2021

Wenzhou Medical University
2021

Abstract Glioblastoma (GBM) is the deadliest form of brain cancer. It a highly angiogenic and immunosuppressive malignancy. Although immune checkpoint blockade therapies have revolutionized treatment for many types cancer, their therapeutic efficacy in GBM has been far less than expected or even ineffective. In this study, we found that genomic signature glioma-derived endothelial cells (GdEC) correlates with an state poor prognosis patients glioma. We established vitro model GdEC...

10.1158/2326-6066.cir-22-0872 article EN Cancer Immunology Research 2023-08-04

<div>Abstract<p>Glioblastoma (GBM) is the deadliest form of brain cancer, characterized as a highly angiogenetic and immunosuppressive malignancy. Although immune checkpoint blockades have revolutionized cancer therapy, their therapeutic efficacy in GBM has been far less than expected or even ineffective. Here, we reveal that genomic signature glioma-derived endothelial cells (GdECs) correlates with an state poor prognosis glioma patients. In vitro model GdECs differentiation...

10.1158/2326-6066.c.6864860.v2 preprint EN 2024-09-16

<div>Abstract<p>Glioblastoma (GBM) is the deadliest form of brain cancer. It a highly angiogenic and immunosuppressive malignancy. Although immune checkpoint blockade therapies have revolutionized treatment for many types cancer, their therapeutic efficacy in GBM has been far less than expected or even ineffective. In this study, we found that genomic signature glioma-derived endothelial cells (GdEC) correlates with an state poor prognosis patients glioma. We established...

10.1158/2326-6066.c.6864860 preprint EN 2023-10-04

<div>Abstract<p>Glioblastoma (GBM) is the deadliest form of brain cancer. It a highly angiogenic and immunosuppressive malignancy. Although immune checkpoint blockade therapies have revolutionized treatment for many types cancer, their therapeutic efficacy in GBM has been far less than expected or even ineffective. In this study, we found that genomic signature glioma-derived endothelial cells (GdEC) correlates with an state poor prognosis patients glioma. We established...

10.1158/2326-6066.c.6864860.v1 preprint EN 2023-10-04
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