A5056699717- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neonatal Respiratory Health Research
- Tryptophan and brain disorders
- Respiratory viral infections research
- Neuroinflammation and Neurodegeneration Mechanisms
- Telomeres, Telomerase, and Senescence
- Autophagy in Disease and Therapy
- Nitric Oxide and Endothelin Effects
- Genomics, phytochemicals, and oxidative stress
- Birth, Development, and Health
- Tannin, Tannase and Anticancer Activities
- Medical and Biological Ozone Research
Pontifícia Universidade Católica do Rio Grande do Sul
2015-2023
Acute viral bronchiolitis by Respiratory Syncytial Virus (RSV) is the most common respiratory illness in children first year of life. RSV generates large numbers hospitalizations and an important burden to health systems. Neutrophils their products are present airways RSV-infected patients who developed increased lung disease. Neutrophil Extracellular Traps (NETs) formed release granular nuclear contents neutrophils extracellular space response different stimuli recent studies have proposed...
Neutrophil extracellular traps (NETs) are a combination of DNA fibers and granular proteins, such as neutrophil elastase (NE). NETs released in the space response to different stimuli. Carrageenan is sulfated polysaccharide extracted from Chondrus crispus , marine algae, used for decades research its potential induce inflammation animal models. In this study, we show first time that carrageenan injection can NET release mouse model acute peritonitis. induced by viable neutrophils with NE...
ABSTRACT The aim of this study is to evaluate the response an inflammatory stimulus in mice exposed LPS‐induced neonatal stress at different ages and sexes. Balb/c were submitted intraperitoneal injections on postnatal days 3 10 with lipopolysaccharide (nLPS) or saline solution (nSal). At 21 60 days, either was injected induced by injection 1% carrageenan. Inflammatory cytokines, reactive oxygen species, neutrophil extracellular traps (NETs) production measured peritoneal fluid. can reduce...
Abstract Background: Cocaine-use disorder (CUD) has been associated with early life adversity and activated cellular immune responses. Women are most vulnerable to complications from chronic substance disorders, generally presenting an intense feeling of abstinence consuming significant drug amounts. Here, we investigated neutrophil functional activities in CUD, including the formation extracellular traps (NETs) related intracellular signalling. We also role stress inflammatory profiles....