A5101655904- Energy, Environment, Economic Growth
- Esophageal Cancer Research and Treatment
- Melanoma and MAPK Pathways
- Synthesis and biological activity
- Computational Drug Discovery Methods
- Environmental Impact and Sustainability
- Esophageal and GI Pathology
- Cholinesterase and Neurodegenerative Diseases
- Energy, Environment, and Transportation Policies
- Fibroblast Growth Factor Research
- Urban Transport and Accessibility
- Head and Neck Cancer Studies
- Pelvic floor disorders treatments
- Medical Research and Treatments
- RNA modifications and cancer
- Regional Economic and Spatial Analysis
- Proteoglycans and glycosaminoglycans research
- Cancer Mechanisms and Therapy
- Agricultural risk and resilience
- Wound Healing and Treatments
- Advanced Breast Cancer Therapies
- Skin and Cellular Biology Research
- Remote Sensing and Land Use
- Agricultural Innovations and Practices
- Fungal Biology and Applications
Zhengzhou University
2007-2025
Tianjin Medical University
2025
University of Science and Technology of China
2025
Zhejiang A & F University
2025
Zhengzhou Business University
2007-2024
Suzhou Municipal Hospital
2023
Nanjing Medical University
2023
Wuhan No. 7 Hospital
2023
Southern Medical University
2012-2021
Zhujiang Hospital
2012-2021
A number of vitamins and minerals have been shown to influence carcinogenesis in experimental animals. In humans, epidemiologic evidence suggests that intake fruits vegetables may reduce risk esophageal other cancers. Vitamins these foods contribute the reduced cancer risk. The people Linxian, China, persistently low multiple nutrients exhibit one world's highest rates esophageal/gastric cardia cancer, with an exceptionally high dysplasia. To determine whether supplementation among persons...
Abstract Inclusive finance has the potential to impact CO 2 emissions resulting from energy activities by influencing regional economic behavior. To explore this relationship, research makes use of panel data covering 30 Chinese provinces between 2004 and 2017. Through utilization empirical methods, including dynamic model, DIFF-GMM mediating effect moderating study examines direction mechanisms influence financial inclusion on various aspects in China. The findings demonstrate that...
Abstract With growing concerns over resource depletion and environmental degradation, the role of high-speed railways in fostering a transition towards sustainable energy sources has gained prominence. Against this background, we treat opening as quasi-natural study, analyze data from Chinese industrial enterprises 285 prefecture-level cities to investigate impact on sustainability, specifically focusing fossil fuel consumption carbon emissions. Our results unequivocally demonstrate that...
In the relentless pursuit of quantum computational advantage, we present a significant advancement with development Zuchongzhi 3.0. This superconducting computer prototype, comprising 105 qubits, achieves high operational fidelities, single-qubit gates, two-qubit and readout fidelity at 99.90%, 99.62%, 99.13%, respectively. Our experiments an 83-qubit, 32-cycle random circuit sampling on 3.0 highlight its superior performance, achieving 1×10^{6} samples in just few hundred seconds. task is...
Transforming growth factor‐β1 is a well‐known fibrogenic cytokine produced by many types of cells including dermal fibroblasts. To investigate whether this involved in development hypertrophic scar, transforming gene expression was evaluated small skin samples. Because sufficient quantity normal from patients with scar not readily available, reverse transcription‐polymerase chain reaction technique used. Quantitation difficult partly due to the lack suitable complementary RNA standards. We...
Abstract A series of 51 biopsies derived from the same number patients with established invasive squamous‐cell carcinoma esophagus in Linxian, a high‐risk area for esophageal cancer China, were analyzed histologically and by situ DNA hybridization to demonstrate human papillomavirus (HPV) infection. Epithelial changes suggesting HPV infection within or adjacent lesions found 25 cases (49.0%). Esophageal morphology showed both flat (25 cases) inverted condylomas (2 resembling those genital...
Under the peer effect theory, this study examines impact of environmental regulation on sulfur dioxide emissions and investigates existence effects in governance mechanisms. Using panel data from 285 prefecture-level cities China 2008 to 2019, a spatial econometric model reveals that significantly reduces local discharge while exhibiting positive spillover surrounding regions, reflecting “beggar-thy-neighbor” dilemma China. The confirms presence regulation, supporting combination ‘top-down’...
A novel class of hydroxycoumarin derivatives were found to be potent α-glucosidase inhibitors. Their syntheses reported and the structure−activity relationship was established. Kinetic enzymatic assays indicated that compound 10 a slow-binding noncompetitive inhibitor with Ki value 589 nM, while 11 competitive 4.810 μM. Among all studied, compounds exhibited highest activities, specific inhibitors α-glucosidase, could exploited as lead for development Compounds also selected further...
Based on panel data of 285 cities in China at the prefecture level and above from 2005 to 2020, this paper aims study nexus between industrial co-agglomeration carbon emissions dual perspectives including space time. It adopts multiple approaches a dynamic general method moment, quantile regression model, threshold spatial Durbin model. The non-spatial empirical results support establishment effect imbalance effect. indicate that poses dramatic stimulating urban emissions, its spillover...
Pakistan is listed among the countries that are extremely vulnerable to climate changes and it has experienced several climatic natural disaster shocks with adverse impacts on its agricultural sector farmers livelihoods. This study investigates adaptation change as a means of farm survival exit in by using panel datasets empirically employs Multinomial Logit Model (MLN) Theory Planned Behavior (TPB). The results reveal, first, experience significantly increases likelihood decreases exit....
Linxian, China, has one of the highest rates esophageal cancer in world. Other authors have described high prevalences histologic esophagitis, atrophy, and dysplasia Linxian suggested that these findings may represent precancerous lesions this population. In 1987, a new endoscopic survey allowed to make an independent study histology Linxian.There were 1567 satisfactory squamous biopsies available from 754 patients. These classified as normal, acanthosis, dysplasia, or cancer.Classified by...
Background. Linxian is the highest endemic area of esophageal squamous cell carcinoma (ESCC) in China and one incidence areas world. The relationship p53 protein accumulation to geographic variation, pathologic findings, prognosis has not been investigated extensively. Methods. Formalin fixed, paraffin embedded ESCC tissues from 100 patients who underwent esophagectomy between 1973 1983 were immunostained by using monoclonal antibody pAB1801. Results. overexpression was observed 41 (87.2%)...
Abstract Linxian, China, has one of the highest esophageal‐cancer mortality rates in world. In 1983, esophageal balloon‐cytology screening was performed to identify subjects eligible for 2 nutrition‐intervention trials Linxian; 12,877 had cytology slides which were satisfactory diagnosis. Of 12,649 with squamous‐cell diagnoses, 31% normal by Chinese cytologic criteria; 38% showed hyperplasia; 21% dysplasia 1; 6% 2; 2% near‐cancer; and cancer. 1,471 columnar‐cell 31 % normal; 44% 16% 4% 3%...
The β-subunit of human choriogonadotropin (hCG) has two complex type N-linked and four O-linked carbohydrate chains. To further evaluate the specificity moiety on hCG function, we have expressed β subunit in baculovirus insect cell system to modify its structures. recombinant (rhCG β) was efficiently secreted medium purified homogeneity by immunoaffinity chromatography using a highly specific monoclonal antibody against β. established sodium dodecyl sulfate-polyacrylamide gel electrophoresis...
A series of 80 esophageal cytologic specimens derived from the same number patients with previously diagnosed squamous cell dysplasia esophagus were examined for presence human papillomavirus (HPV) infection by filter in situ hybridization (FISH), using a mixed DNA probe containing HPV types 11, 16, and 18. All came an area at high risk cancer China. total 53 cases (66.3%) demonstrated as HPV-DNA-positive. was detected 22.2% (2 9) without atypia, 50% (3 6) mild dysplasia, 80.6% (25 31)...