A5100634274- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Folate and B Vitamins Research
- Advanced biosensing and bioanalysis techniques
- Eicosanoids and Hypertension Pharmacology
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Pituitary Gland Disorders and Treatments
- Electrochemical sensors and biosensors
- PI3K/AKT/mTOR signaling in cancer
- Growth Hormone and Insulin-like Growth Factors
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Phytochemistry and biological activity of medicinal plants
- Genomic variations and chromosomal abnormalities
- Advanced Biosensing Techniques and Applications
- Cancer Mechanisms and Therapy
- Ginseng Biological Effects and Applications
- Conducting polymers and applications
- Chromatin Remodeling and Cancer
- Extracellular vesicles in disease
- Botany, Ecology, and Taxonomy Studies
- Microbial Community Ecology and Physiology
Hubei Zhongshan Hospital
2025
Wuhan University
2025
Southeast University
2010-2025
State Key Laboratory of Digital Medical Engineering
2025
Lanzhou University
2023-2024
Third Affiliated Hospital of Sun Yat-sen University
2013-2023
Sun Yat-sen University
2013-2023
Key Laboratory of Guangdong Province
2023
Sichuan Cancer Hospital
2023
University of Electronic Science and Technology of China
2023
Circular RNAs (circRNAs) are associated with cancer progression and metastasis, although little is known about their role in lung adenocarcinoma (LAC). In the present study, microarrays were first used to screen for tumour-specific circRNA candidates LAC tissue. Thirty-nine circRNAs found be up-regulated 20 down-regulated (fold change > 2.0). Among them, hsa_circ_0013958 was further confirmed all of tissues, cells plasma. addition, levels TNM stage (P = 0.009) lymphatic metastasis 0.006)....
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and has a poor prognosis. Pituitary tumor transforming gene 1 (PTTG1) highly expressed in HCC, suggesting it could play an important role hepatocellular carcinogenesis. Here, we evaluated impact PTTG1 deficiency on HCC development using diethylnitrosamine (DEN)-induced mouse model hepatitis B virus (HBV) regulatory X protein (HBx)-induced spontaneous model. significantly suppressed DEN- HBx-induced...
Exosome-delivered circular RNAs (circRNAs) are recognized as a key mechanism that regulates osteosarcoma (OS) progression. The purpose of this study is to discover the role novel circRNA hsa_circ_0000116 from exosomes in OS Transmission electron microscopy, nanoparticle tracking analysis, and western blotting were used identify isolated two cell lines (HOS MG-63). After coculturing with cells transfecting knockdown vector into cells, function experiments, including counting kit-8, wound...
Depression is one of the most severe mental disorders, and facing challengeable lack objective diagnosis, as well early screening predicting treatment responses. Consequently, developing sensitive, efficient, convenient, accurate, real-time detection technology for depression markers earns more attention. Electrochemical immunosensor, a promising method analyzing disease markers, selectively binds target antigen with antibodies (Abs), converting biological signal antigen-antibody recognition...
The content of γ -aminobutyric acid (GABA) in human serum has been proved to be closely related depression, so the rapid, sensitive, highly selective and accurate determination GABA is great significance for objective diagnosis depression. In this study, a molecularly imprinted electrochemical sensor based on high-performance magnetically functionalized reduced graphene oxide (MRGO) was constructed sensitive detection depressed mice. Using MRGO modified flexible electrode (ITO-PET),...
A Gram-stain-negative, rod-shaped, motile bacterial strain, designated 3-5-3T, was isolated from maize-cultivated soil artificially contaminated with cadmium, in Nanyang, Henan Province, China. Strain 3-5-3T oxidase- and catalase-positive. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain affiliated the genus Paenibacillus most closely related to anaericanus MH2T (96.5 % similarity). The average nucleotide identity digital DNA-DNA hybridization values between...
<p>Supplemental Methods and Materials</p>
<p>Supplementary Figures</p>
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<p>Supplemental Table</p>
<p>Supplemental Methods and Materials</p>
The hedgehog (HH) signaling pathway is abnormally activated in glioblastoma (GBM); thus, its downstream effector GLI1 may be a suitable target for the treatment of GBM. aim present study was to evaluate antitumor activities novel compound, FL34, GBM through inhibition GLI1.The effect FL34 on suppressing proliferation, angiogenesis, and invasion cells investigated vitro using invasion, tube formation, flow cytometry, dual luciferase, reverse transcription-quantitative polymerase chain...
<p>Supplemental Table</p>
<p>Supplemental Methods and Materials</p>
<p>Supplementary Figures</p>
<p>Supplementary Figures</p>
<div>Abstract<p>Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and has a poor prognosis. Pituitary tumor transforming gene 1 (PTTG1) highly expressed in HCC, suggesting it could play an important role hepatocellular carcinogenesis. Here, we evaluated impact PTTG1 deficiency on HCC development using diethylnitrosamine (DEN)-induced mouse model hepatitis B virus regulatory X protein (HBx)-induced spontaneous model. significantly suppressed DEN-...