- Pediatric Urology and Nephrology Studies
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Dermatology and Skin Diseases
- Gastrointestinal motility and disorders
- Ureteral procedures and complications
- Urinary Bladder and Prostate Research
- Respiratory and Cough-Related Research
- Respiratory Support and Mechanisms
- Urinary Tract Infections Management
- Fetal and Pediatric Neurological Disorders
- Sexual function and dysfunction studies
- Spinal Dysraphism and Malformations
- Cell Adhesion Molecules Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intestinal and Peritoneal Adhesions
- Cerebrospinal fluid and hydrocephalus
University Medical Center Groningen
2024-2025
University of Groningen
2024-2025
University Medical Center Utrecht
1999
Studies of bronchoalveolar lavage (BAL) fluid from patients with allergic asthma have demonstrated active migration eosinophils into the bronchial lumen after allergen challenge. The mechanisms mediating this eosinophil infiltration and cell activation are largely unexplained. expression several cell-surface molecules was measured on derived blood BAL 4 h an allergen-induced early asthmatic reaction in order to find indications for a role these during extravasation compartment. Nine...
To analyze comprehensively the incidence, antenatal ultrasound characteristics and prognostic implications of pop-off mechanisms fetal urinary system in pregnancies with suspected megacystis. This was a retrospective multicenter study megacystis conducted across all academic hospitals The Netherlands. Three were identified: presence an umbilical cord cyst (UCC), extravasation urine into intraperitoneal space (ascites) or perirenal subcapsular (urinoma), megaureter/ureterocele. Cases that...
Abstract Introduction and Hypothesis Pelvic floor damage can contribute to pelvic dysfunction, including constipation. Most studies focus on constipation during pregnancy, whereas information regarding the mode of delivery in relation is limited. We hypothesise that women with a history vaginal report more often than caesarean section. Methods This was retrospective cross-sectional multicentre study conducted Netherlands. All included patients ( n = 2,643) completed Groningen Defecation...
Summary Background Atopic dermatitis (AD) is often associated with allergic asthma (AA). Inhalation of allergens influences the activity AA but effect on skin in AD unclear. Objectives We evaluated degree bronchial hyperresponsiveness to methacholine eight patients (AD + ) and without – studied cutaneous responses after allergen inhalation challenge. Methods All were treated hospital for their eczema tar ointment (pix liquida) orally administered antihistamines (mean stay 37 days). After...
It is unclear whether the presence and severity of atopic dermatitis (AD) predictive for occurrence early late asthmatic responses to inhaled allergens. The aim this study was compare bronchial effects allergen inhalation challenge in allergic asthma (AA) dermatitis. We therefore studied these in: nine patients with mild-to-moderate AA without AD; eight mild severe AD AA; AA. Allergen performed by inhaling doubling doses until dose provoking a 20% fall forced expiratory volume one second...
Eosinophils play an important role in the pathogenesis of asthma. Several pro-inflammatory responses eosinophils are primed vivo this disease. The aim present study was to investigate whether regular antiasthma treatment could modulate priming-sensitive cytotoxic mechanisms human eosinophils. In a randomized, two-centre, double-blind parallel group study, effect 8 weeks with salmeterol xinafoate 50 microg b.i.d., beclomethasone dipropionate 400 b.i.d. or both on pulmonary function and...
Importance Urinary incontinence, fecal and constipation frequently manifest are risk factors for one another. Studies investigating the association between parity problems in urinary continent incontinent women lacking. Objectives The aim of this study was to examine whether differs women. Study Design This a cross-sectional, retrospective questionnaire-based study. population representation general Dutch female (n = 5,670), including nulliparous 2,790) parous 2,880). Data were collected...