A5039597110- SARS-CoV-2 and COVID-19 Research
- Polysaccharides Composition and Applications
- Polysaccharides and Plant Cell Walls
- Ecology and biodiversity studies
- Peatlands and Wetlands Ecology
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Advanced Proteomics Techniques and Applications
- Bat Biology and Ecology Studies
- Erythrocyte Function and Pathophysiology
- Plant Pathogens and Fungal Diseases
- Zoonotic diseases and public health
- Cellular transport and secretion
- Marine and environmental studies
- Plant Reproductive Biology
Imperial College London
2023
The University of Melbourne
2012
Australian Research Council
2012
There has been limited characterisation of bat-borne coronaviruses in Europe. Here, we screened for 48 faecal samples from 16 the 17 bat species breeding UK, collected through a rehabilitation and conservationist network. We recovered nine complete genomes, including two novel coronavirus species, across six species: four alphacoronaviruses, MERS-related betacoronavirus, closely related sarbecoviruses. demonstrate that at least one these sarbecoviruses can bind use human ACE2 receptor...
Plant cell walls are complex matrixes of heterogeneous glycans which play an important role in the physiology and development plants provide raw materials for human societies (e.g. wood, paper, textile biofuel industries)1,2. However, understanding biosynthesis function these components remains challenging. Cell wall chemically conformationally diverse due to complexity their building blocks, glycosyl residues. These form linkages at multiple positions differ ring structure, isomeric or...
Plant cell walls are complex matrixes of heterogeneous glycans which play an important role in the physiology and development plants provide raw materials for human societies (e.g. wood, paper, textile biofuel industries)1,2. However, understanding biosynthesis function these components remains challenging. Cell wall chemically conformationally diverse due to complexity their building blocks, glycosyl residues. These form linkages at multiple positions differ ring structure, isomeric or...
Abstract There has been limited characterisation of bat-borne coronaviruses in Europe. Here, we screened for 48 faecal samples from 16 the 17 bat species breeding UK, collected through a rehabilitation and conservationist network. We recovered nine (two novel) complete genomes across six species: four alphacoronaviruses, MERS-related betacoronavirus, closely related sarbecoviruses. demonstrate that at least one these sarbecoviruses can bind use human ACE2 receptor infecting cells, albeit...
The world’s peatlands are our largest terrestrial carbon store whilst also providing a sustainable source of drinking water, haven for wildlife and storing record past. England Peat Map aims to provide baseline maps the extent, depth, condition peaty soils in by 2024. This will enable targeting future restoration, support nature recovery, improve greenhouse emissions reporting natural capital accounting.The be created using combination multi-scale Earth observation imagery...
Abstract We describe a two‐dimensional polyacrylamide gel electrophoresis (2‐D PAGE)‐based approach for detecting and quantifying secreted recombinant proteins in media conditioned by baby hamster kidney (BHK) cells. Seven were analyzed this system: leptin, thrombopoietin, thrombin, glycoprotein 130, soluble interleukin‐2 receptor, two novel sequences obtained from sequence database searches. BHK cells transfected with plasmids encoding each of these proteins, empty (control cells),...