A5067396970- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Innovative Microfluidic and Catalytic Techniques Innovation
- Electrospun Nanofibers in Biomedical Applications
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Cell Image Analysis Techniques
- Wound Healing and Treatments
- Cancer Cells and Metastasis
- Neuroscience and Neural Engineering
- biodegradable polymer synthesis and properties
- Orthopaedic implants and arthroplasty
- Planarian Biology and Electrostimulation
- Graphene and Nanomaterials Applications
- Cellular Mechanics and Interactions
Sungkyunkwan University
2019-2024
The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged as a powerful approach in cancer research and drug development. This review provides an extensive examination the diverse biofabrication methods employed to create mini-tissues, including 3D bioprinting, spheroids, microfluidic systems, self-assembly techniques using cell-laden hydrogels. Furthermore, it explores various approaches for fabricating organ-on-a-chip platforms. paper highlights synergistic...
Abstract Human adipose-derived stem cell spheroids have been widely used in the treatment or regeneration of damaged skin tissues, and their success is believed to be due part angiogenic factors released from spheroids. To achieve sustained release bioactive components implanted within a defective area, use biocompatible scaffolding biomaterial required. In this study, we developed an alginate-based structure, which was processed using three-dimensional printing electrospinning for as...
Rationale: Cell spheroids have shown great promise as tools for creating effective three-dimensional (3D) tissue models, facilitating reconstruction and organoid development, due to their high cell density efficient cellular interactions.However, a significant challenge persists in large-scale structures with 3D geometrical architecture using spheroids, the continual condensation reorganization of cells environments.Methods: The spherical aggregates (pseudo-cell spheroids) or macroscale were...
A spheroid is an aggregation of single cells with structural and functional characteristics similar to those 3D native tissues, it has been utilized as one the typical in vitro three-dimensional (3D) cell models. Scaffold-free spheroids provide outstanding reflection tissue complexity a vivo-like environment, but they can neither fabricate realistic macroscale complex structures without avoiding necrosis nor receive direct external stimuli (i.e., from mechanical or topographical cues). Here,...
Abstract Bioprinting is a widely used technique for creating three-dimensional, complex, and heterogeneous artificial tissue constructs that are biologically biophysically similar to natural tissues. The skin composed of several layers including the epidermis, basement membrane (BM), dermis. However, unique undulating structure membranes (i.e. rete ridges) function BM have not been extensively studied in fabrication engineered substitutes. In this study, novel substitute incorporating an...
Topographical cues are one of the prerequisites for successful regeneration muscle tissue. However, fabrication methods using three-dimensional (3D) bioprinters limited by simple nozzle-based extrusion or uncontrollability photo-reactive systems. Hence, most studies on inducing topographical were focused two-dimensional (2D) surface structures, and based imprinting soft-lithography processes. Although 2D patterned surfaces provide outstanding insight into optimal architectures facilitating...