A5055529349- Gastric Cancer Management and Outcomes
- Ferroptosis and cancer prognosis
- Bioinformatics and Genomic Networks
- RNA modifications and cancer
- Psoriasis: Treatment and Pathogenesis
- Angiogenesis and VEGF in Cancer
- Metastasis and carcinoma case studies
Army Medical University
2024
Sichuan University of Science and Engineering
2023
To evaluate the long-term outcomes and prognostic factors of locally advanced gastric cancer with serosa-invasion.
Objective: This study was to comprehensively explore key genes in lung adenocarcinoma (LUAD) using bioinformatics methods and analyze their biological functions, aiming provide a theoretical basis for diagnosis treatment of LUAD. Methods: Gene chip datasets GSE2088 GSE32863 were downloaded from the GEO database. Differential expression (DEGs) screened GEO2R. GO KEGG pathway enrichment analyses performed DAVID A protein-protein interaction (PPI) network constructed STRING database Cytoscape...
14634 Background: Inhibition of angiogenesis is a promising approach to treat cancer. Endostatin, the COOH-terminal proteolytic fragment basement membrane component collagen XVIII, represents one most potent endogenous angiogenic inhibitors. Recombinant human endostatin adenoviruses (Ad-hE), encapsulated with (Ad-hE/Lipo) and without liposome, were evaluated for their potential anti-tumor activity. Methods: MTT colorimetric assay was used evaluate inhibition on umbilical vein endothelial...