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Research Areas
- Immune cells in cancer
- Inflammasome and immune disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Kunming Medical University
2024
Abstract Excessive host immune responses contribute to severe malaria with high mortality. Here, we show that PRL2 in innate cells is highly related experimental disease progression, especially the development of murine malaria. In absence myeloid cells, Plasmodium berghei infection results augmented lung injury, leading significantly increased Intravital imaging revealed greater neutrophilic inflammation and NET formation lungs conditional knockout mice. Depletion neutrophils prior onset...
10.1038/s41467-024-45210-5
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cc-by
Nature Communications
2024-01-29
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