A5050549372- Natural product bioactivities and synthesis
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Plant biochemistry and biosynthesis
Central South University
2024
Abstract Ginsenosides, the primary bioactive constituents in ginseng (Panax ginseng), possess substantial pharmacological potential and are high demand market. The plant hormone methyl jasmonate (MeJA) effectively elicits ginsenoside biosynthesis P. ginseng, though regulatory mechanism remains largely unexplored. NAC transcription factors critical intricate networks participate numerous physiological activities. In this study, we identified a MeJA-responsive factor gene, PgNAC72, from...
Ginseng has been used extensively for medicinal purposes, with suggested utility indications as diverse diabetes, cardiovascular disease and cancer. Herein we report the discovery characterization of 20(S)-25-OCH3-PPD, a ginsenoside that inhibits growth survival cancer cells. The novel dammarane triterpene sapogenin (C31H56O4; molecular weight 492) was isolated from total hydrolyzed saponins extracted leaves Panax notoginseng using conventional reverse-phase silica gel chromatography. Based...