Nina Leão Marques Valente

ORCID: 0009-0005-6881-8866
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About
Contact & Profiles
Research Areas
  • Posttraumatic Stress Disorder Research
  • Child Abuse and Trauma
  • Memory and Neural Mechanisms
  • Child and Adolescent Psychosocial and Emotional Development
  • Stress Responses and Cortisol
  • Resilience and Mental Health
  • Psychotherapy Techniques and Applications
  • Family and Disability Support Research
  • Childhood Cancer Survivors' Quality of Life
  • Porphyrin Metabolism and Disorders
  • Treatment of Major Depression
  • Enzyme Structure and Function
  • Sex and Gender in Healthcare
  • Fungal and yeast genetics research
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Mycotoxins in Agriculture and Food
  • Plant Pathogens and Fungal Diseases
  • Psychology and Mental Health
  • Adolescent and Pediatric Healthcare
  • Educational and Psychological Assessments
  • Family Support in Illness
  • Biochemical Acid Research Studies

BOKU University
2022-2023

Universidade Federal de São Paulo
2008-2016

Topiramate might be effective in the treatment of posttraumatic stress disorder (PTSD) because its antikindling effect and action both inhibitory excitatory neurotransmitters. Open-label studies few controlled trials have suggested that this anticonvulsant may therapeutic potential PTSD. This 12-week randomized, double-blind, placebo-controlled clinical trial will compare efficacy topiramate with placebo study tolerability PTSD.Seventy-two adult outpatients DSM-IV-diagnosed PTSD recruited...

10.1186/1471-244x-9-28 article EN cc-by BMC Psychiatry 2009-05-29

Os autores discutem, a partir do conceito evolutivo, como resposta de estresse, nas suas possibilidades fuga e luta imobilidade tônica, pode levar uma nova compreensão etiológica transtorno estresse pós-traumático. Através da análise dos agrupamentos sintomas desse diagnóstico - revivência, evitação hiperexcitação -, procuram correlacionar os achados neurobiológicos evolutivos. As descobertas atuais sobre genética pós-traumático são resumidas colocadas nessa perspectiva evolutiva, dentro...

10.1590/s0101-81082008000200008 article PT Revista de Psiquiatria do Rio Grande do Sul 2008-01-01

The oxidative decarboxylation of coproheme to form heme b by decarboxylase is a stereospecific two-step reaction. In the first step, propionate at position two (p2) cleaved off pyrrole ring A vinyl group this position. Subsequently, four (p4) on B and formed. study, we attempted engineer from Corynebacterium diphtheriae alter stereospecificity By introducing tyrosine residue in proximity 4, were able create new radical center active site. However, artificial Tyr183• could not be shown...

10.3389/fbioe.2021.807678 article EN cc-by Frontiers in Bioengineering and Biotechnology 2022-01-24
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