A5049830776- Neutropenia and Cancer Infections
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Public Health in Brazil
- Hematological disorders and diagnostics
- Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
Centro Universitário do Maranhão
2024
IPO Porto
2019
Triple-negative breast cancer (TNBC) is a subtype caused by mutation in the BRCA 1 gene, which responsible for components of DNA. In this histological type cancer, estrogen, progesterone, and HER2 protein receptors are absent, making it very aggressive, with great metastatic potential lack therapies, requiring surgical intervention neoadjuvant approach. way, study aims to list discuss effectiveness different treatments triple-negative cancer. This systematic review A search was carried out...
Abstract Background: Optimal management of bone marrow metastasis (BMM) in advanced breast cancer (ABC) remains unknown. Associated severe cytopenias often urge treatment, but they are also a challenging factor for delivering chemotherapy (CT). Since BMM ABC is infrequent, available data scarce. Aim: Clinical and prognostic characterization patients with its management; evaluation the effectiveness treating more myelosuppressive CT regimen (that we hypothesized that could be active BMM) Vs....